论坛 › 河南 › 世界艾滋病大会：世界首例经过药物治疗痊愈的艾滋病病人！

m5k1umn 发表于 2024-6-28 11:16:54

世界艾滋病大会：世界首例经过药物治疗痊愈的艾滋病病人！

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/7FibmWHdZgwFn2yr2Kbqe6MDnKlsDyFs9wXAzv9D5jH16w1Pia1C41Mv6gdBd0syOYrFq7D4WiajxwvI3kTG6Vtmw/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">本公众号由</span><span style="color: black;">云南省防治艾滋病局</span><span style="color: black;">主办，<span style="color: black;">倘若</span>您还未关注，请点击上方蓝色“</span><span style="color: black;">云南防艾</span><span style="color: black;">”进行关注。</span></p><img src="https://mmbiz.qpic.cn/mmbiz_png/7FibmWHdZgwFgq4rbkcL37f4JWf9bjXvhK2DURDSuNpKHiaFTHOHDJs9d94ZNXs3YX4MVO9mbx46TzDltCCC9ibmQ/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">这位34岁的巴西病患2012年被诊断出感染艾滋病毒（HIV）。他在这项<span style="color: black;">科研</span>中接受数种抗反转录病毒<span style="color: black;">药品</span>（Antiretroviral Therapy, ART）治疗48周，<span style="color: black;">瞧瞧</span><span style="color: black;">是不是</span>能帮他去除<span style="color: black;">身体</span>病毒。</span></strong><span style="color: black;"><strong style="color: blue;"><span style="color: black;">他<span style="color: black;">迄今</span>已超过57周未接受治疗，但接受艾滋病毒检测<span style="color: black;">始终</span>呈阴性反应。</span></strong></span></p><img src="https://mmbiz.qpic.cn/mmbiz_png/7FibmWHdZgwFgq4rbkcL37f4JWf9bjXvhjUfU9qYkibwVR3yibvTwumBJUWHvY8Via6Y8YaWJP9yjFekIDSB7eKbZw/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;"><span style="color: black;">科研</span>人员7月<span style="color: black;">7</span>日<span style="color: black;">暗示</span>，巴西一位艾滋病患接受<span style="color: black;">运用</span>多种抗病毒<span style="color: black;">药品</span>鸡尾酒疗法后，一年多来未再<span style="color: black;">显现</span>病症，可能是世界首位未经骨髓移植就<span style="color: black;">实质</span>上痊愈的<span style="color: black;">病人</span>，或许是艾滋病治疗的重大突破。</span><span style="color: black;"><span style="color: black;">全世界</span>如今有数以千万计艾滋病毒感染者，虽然如今感染者不像以往<span style="color: black;">同样</span>等于被判了死刑，但病患<span style="color: black;">必要</span>终生服药。近年<span style="color: black;">仅有</span>两位代号「柏林」（Berlin）与「伦敦」（<span style="color: black;">London</span>）的男性病患，在接受用来治疗癌症的高<span style="color: black;">危害</span>干细胞骨髓移植手术后似乎治愈。</span><span style="color: black;">如今一支国际<span style="color: black;">科研</span>团队的<span style="color: black;">科研</span>人员认为，<span style="color: black;">她们</span>或许已让第3位病人接受<span style="color: black;">区别</span><span style="color: black;">药品</span>疗程后<span style="color: black;">再也不</span><span style="color: black;">显现</span>感染徵象。这位<span style="color: black;">34</span>岁的巴西病患<span style="color: black;">2012</span>年被诊断出感染艾滋病毒（<span style="color: black;">HIV</span>）。他在这项<span style="color: black;">科研</span>中接受数种抗反转录病毒<span style="color: black;">药品</span>（<span style="color: black;">Antiretroviral Therapy, ART</span>）治疗<span style="color: black;">48</span>周，<span style="color: black;">瞧瞧</span><span style="color: black;">是不是</span>能帮他去除<span style="color: black;">身体</span>病毒。他<span style="color: black;">迄今</span>已超过<span style="color: black;">57</span>周未接受治疗，但接受艾滋病毒检测<span style="color: black;">始终</span>呈阴性反应。</span>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/ZyJwI3Ld5HzIb1rfibG120fSlYd0pP6lSvPQ8QhgEwgkeUWtZ2hFPdSe5WxZp76UQLx2XRNHZicib30TX5DFDcS1w/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">巴西圣保罗大学（University of Sao Paulo）传<span style="color: black;">患病</span>专家狄亚士（<span style="color: black;">Ricardo Diaz</span>）说，这位病患可被视为已摆脱艾滋病毒。</span><span style="color: black;">以上内容是“巴西<span style="color: black;">HIV</span>治愈<span style="color: black;">病人</span>”或“第三例<span style="color: black;">HIV</span>治愈<span style="color: black;">病人</span>”的<span style="color: black;">报告</span>，今天这个视频提前上传到了大会视频网站，<span style="color: black;">导致</span>了<span style="color: black;">媒介</span>广泛<span style="color: black;">报告</span>。这个病例来自于巴西<span style="color: black;">2014</span>年开展的<span style="color: black;">SPARC-7</span>临床<span style="color: black;">实验</span>。该治愈<span style="color: black;">实验</span>给予了<span style="color: black;">30</span>名受试者应用了<span style="color: black;">DTG + CCR5</span><span style="color: black;">控制</span>剂<span style="color: black;">Maraviroc +</span>一种储藏库激活剂烟酰胺（<span style="color: black;">NAM</span>）。</span><span style="color: black;">其中一名35岁<span style="color: black;">病人</span>（<span style="color: black;">ID 3.2</span>），<span style="color: black;">2012</span>年<span style="color: black;">10</span>月确诊<span style="color: black;">HIV</span>感染，<span style="color: black;">2012</span>年<span style="color: black;">12</span>月<span style="color: black;">起始</span><span style="color: black;">AZT/3TC+EFV</span>抗病毒治疗。该<span style="color: black;">病人</span><span style="color: black;">2015</span>年<span style="color: black;">9</span>月进入<span style="color: black;">以上</span><span style="color: black;">SPARC-7</span><span style="color: black;">科研</span>，<span style="color: black;">2016</span>年<span style="color: black;">9</span>月<span style="color: black;">科研</span>结束，<span style="color: black;">2019</span>年<span style="color: black;">3</span>月<span style="color: black;">起始</span>实验性停药<span style="color: black;">ATI</span>。<span style="color: black;">病人</span>在<span style="color: black;">实验</span><span style="color: black;">时期</span>，<span style="color: black;">出现</span>了短暂<span style="color: black;">blip</span>，证明储藏库可能被<span style="color: black;">NAM</span>释放。<span style="color: black;">ATI</span>病毒载量不反弹是<span style="color: black;">评估</span><span style="color: black;">HIV</span>治愈的金标准，该<span style="color: black;">病人</span>在<span style="color: black;">ATI</span><span style="color: black;">时期</span>，其病毒载量均检测不到。神奇的是，在<span style="color: black;">ATI</span>之前，<span style="color: black;">NAM</span>治疗之后，这个<span style="color: black;">病人</span><span style="color: black;">HIV DNA</span><span style="color: black;">逐步</span>检测不到，而应用<span style="color: black;">VOA assay</span><span style="color: black;">不可</span>释放出<span style="color: black;">HIV</span>病毒，说明其储藏库<span style="color: black;">逐步</span>消失。更神奇的是，在<span style="color: black;">ATI</span><span style="color: black;">周期</span>患者的<span style="color: black;">HIV</span>抗体<span style="color: black;">逐步</span>转阴。而<span style="color: black;">CD8</span>细胞激活减少。</span><span style="color: black;"><span style="color: black;">然则</span><span style="color: black;">咱们</span>仍然认为进行及早抗病毒治疗<span style="color: black;">非常</span><span style="color: black;">要紧</span>，而应用DTG+Maraviroc<span style="color: black;">能够</span><span style="color: black;">控制</span><span style="color: black;">HIV</span>病毒整合，<span style="color: black;">NAM</span><span style="color: black;">能够</span>激活储藏库，<span style="color: black;">同期</span><span style="color: black;">加强</span><span style="color: black;">T</span>细胞免疫应答。这个病例<span style="color: black;">HIV DNA</span>检测不到，<span style="color: black;">VOA</span><span style="color: black;">没</span>法释放病毒，说明这一<span style="color: black;">病人</span>有可能<span style="color: black;">作为</span><span style="color: black;">第1</span>例经过非异基因造血干细胞移植获得<span style="color: black;">HIV</span><span style="color: black;">长时间</span>缓解的<span style="color: black;">病人</span>。<span style="color: black;">不外</span>，这个<span style="color: black;">病人</span>只是这个队列中的<span style="color: black;">1/30</span>，<span style="color: black;">按照</span>反复提及的<span style="color: black;">Sneller</span><span style="color: black;">科研</span>及<span style="color: black;">RV254</span>等<span style="color: black;">科研</span>，这个<span style="color: black;">病人</span>可能是一个治疗后<span style="color: black;">掌控</span><span style="color: black;">病人</span>，即<span style="color: black;">PTC</span>。而<span style="color: black;">日前</span>只跟踪了<span style="color: black;">ATI 64</span>周，为时尚早，<span style="color: black;">因此呢</span><span style="color: black;">必须</span>继续观察这一<span style="color: black;">病人</span>病毒学指标。</span>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/ZyJwI3Ld5HzIb1rfibG120fSlYd0pP6lS9u9LATHqFbNYkmrtW587LwoKbX8ibfbRGORiaZ8Ssu7iaVNuWqtgGZIMw/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;"><span style="color: black;">源自</span>：世界艾滋病大会、子陵在听歌、白桦林健康<span style="color: black;">新闻</span></span>
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lanbingkj 发表于 2024-9-10 00:16:00

祝福你、祝你幸福、早日实现等。

nykek5i 发表于 昨天 00:18

期待更新、坐等、迫不及待等。

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