吸烟显著影响艾滋病病毒感染者的健康和寿命
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(<span style="color: black;">源自</span>:珲春市疾控中心)</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://q7.itc.cn/q_70/images03/20240329/085a90a6f7394b648b2fff9ec680dd87.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">吸烟有害健康已<span style="color: black;">作为</span>共识,<span style="color: black;">然则</span>吸烟会对艾滋病病毒感染者的健康产生进一步的影响吗?</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">虽然<span style="color: black;">日前</span>尚未见我国关于艾滋病病毒感染者中吸烟比例的调查统计数据,但据美国迈阿密大学的一项调查<span style="color: black;">表示</span>,美国艾滋病病毒感染者吸烟率达到47%,而非艾滋病病毒感染人群的吸烟率仅为25.5%<span style="color: black;"><span style="color: black;">【1】</span></span>,这可能与艾滋病病毒感染人群承受的精神压力大等<span style="color: black;">原因</span><span style="color: black;">相关</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://q0.itc.cn/q_70/images03/20240329/2e91b9186af24cbab6590e52737e3f5a.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">令人担忧的是,许多<span style="color: black;">科研</span><span style="color: black;">发掘</span>,吸烟的艾滋病病毒感染者比不吸烟的艾滋病病毒感染者的预后更差。北加州大学的一项大型<span style="color: black;">科研</span><span style="color: black;">发掘</span>,在20岁的艾滋病病毒感染人群中,吸烟与从不吸烟者的预期寿命差别达到10年<span style="color: black;"><span style="color: black;">【2】</span></span>。另一项针对40岁<span style="color: black;">起始</span>接受抗病毒治疗的艾滋病病毒感染人群的研究<span style="color: black;">发掘</span>,吸烟与从不吸烟者,预期寿命差别为6-7年<span style="color: black;"><span style="color: black;">【3】</span></span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">科研</span>还<span style="color: black;">发掘</span>,感染艾滋病病毒的吸烟者患心脏病的<span style="color: black;">危害</span>几乎是未感染艾滋病病毒的吸烟者的三倍,是感染艾滋病病毒戒烟者的两倍<span style="color: black;"><span style="color: black;">【4】</span></span>。<span style="color: black;">一样</span>,感染艾滋病病毒的吸烟者患慢性阻塞性肺病(COPD)和肺癌的<span style="color: black;">危害</span><span style="color: black;">亦</span>比戒烟者或不吸烟者要高<span style="color: black;">非常多</span><span style="color: black;"><span style="color: black;">【5】</span></span>。</p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">综上,艾滋病病毒感染者戒烟除了能延长预期寿命外,还能降低患癌症、心血管<span style="color: black;">疾患</span>、慢性阻塞性肺病等<span style="color: black;">疾患</span>的<span style="color: black;">危害</span>。<span style="color: black;">因此呢</span>,戒烟是艾滋病病毒感染者延长寿命、<span style="color: black;">加强</span>生活质量的首选。然而,戒烟<span style="color: black;">亦</span>是一个艰难的<span style="color: black;">专题</span>,<span style="color: black;">没</span>论是靠自律和毅力戒烟,还是<span style="color: black;">经过</span><span style="color: black;">药品</span>、电子烟等途径试图达到<span style="color: black;">最后</span>戒烟的目的,艾滋病病毒感染者成功戒烟的比例还不到15%<span style="color: black;"><span style="color: black;">【6】</span></span>。那么,还<span style="color: black;">能够</span>采取<span style="color: black;">那些</span><span style="color: black;">办法</span>来尽可能<span style="color: black;">加强</span>未戒烟艾滋病病毒感染者寿命呢?</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">办法</span>当然有。<span style="color: black;">倘若</span><span style="color: black;">不可</span>完全戒烟,<span style="color: black;">能够</span><span style="color: black;">奋斗</span>减少<span style="color: black;">每日</span>的最大吸烟量,并随着时间的推移<span style="color: black;">逐步</span>减少。一项模型<span style="color: black;">科研</span><span style="color: black;">发掘</span>,<span style="color: black;">针对</span>40岁的艾滋病病毒感染者,<span style="color: black;">连续</span>重度吸烟者的肺癌死亡率接近28~29%,而<span style="color: black;">连续</span>轻度吸烟者(<span style="color: black;">每日</span>5支或更少)的肺癌死亡率约为16.5~19%<span style="color: black;"><span style="color: black;">【7】</span></span>。这一结果虽然比戒烟人群(3.7~8%)和从不吸烟人群(1~2%)仍然高不少,但<span style="color: black;">亦</span><span style="color: black;">表示</span>出了<span style="color: black;">极重</span>的改善。<span style="color: black;">倘若</span><span style="color: black;">不可</span>完全戒烟,那就尽可能减少吸烟量吧!</p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">40岁艾滋病病毒感染者吸烟<span style="color: black;">状况</span>与肺癌死亡率<span style="color: black;">【7】</span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://q6.itc.cn/q_70/images03/20240329/ed5565fe95e74228bf426d95717cc559.png" style="width: 50%; margin-bottom: 20px;"></p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">最后,不论<span style="color: black;">是不是</span>戒烟或减少吸烟量,都<span style="color: black;">意见</span><span style="color: black;">按照</span>高危程度<span style="color: black;">定时</span>做低剂量CT扫描进行肺癌筛查,<span style="color: black;">初期</span><span style="color: black;">发掘</span>和治疗的肺癌比中晚期或一<span style="color: black;">发掘</span>就<span style="color: black;">已然</span>扩散的<span style="color: black;">病人</span><span style="color: black;">存活</span>率要高得多。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">改变的<span style="color: black;">第1</span>步是<span style="color: black;">加强</span><span style="color: black;">认识</span>。<span style="color: black;">倘若</span>您是一名艾滋病病毒感染者,吸烟者请您<span style="color: black;">尽可能</span>戒烟或减少吸烟量,<span style="color: black;">已然</span>戒烟和从不吸烟者请您继续保持。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(梁华 中国疾控艾防中心)</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://q4.itc.cn/q_70/images03/20240329/74cc2849e6f746779e636aa09db68b6e.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">参考文献:</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【1】Asfar T, et al. National Estimates of Prevalence, Time-Trend, and Correlates of Smoking in US People Living with HIV (NHANES 1999-2016). Nicotine Tob Res. 2021;23(8):1308-1317.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【2】Marcus JL, et al. Narrowing the Gap in Life Expectancy Between HIV-Infected and HIV-Uninfected Individuals With Access to Care. J Acquir Immune Defic Syndr. 2016;73(1):39-46.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【3】Krishna P. et al, Impact of Cigarette Smoking and Smoking Cessation on Life Expectancy Among People With HIV: A US-Based Modeling Study, The Journal of Infectious Diseases, 2016; 214(11):1672–1681,</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【4】Perkins MV, et al. Cardiovascular Disease and Thrombosis in HIV Infection. Arterioscler Thromb Vasc Biol. 2023;43(2):175-191.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【5】Hessol NA, et al. Risk of smoking-related cancers among women and men living with and without HIV. AIDS. 2021;35(1):101-114.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【6】Shuter Jonathan, et al. Harm reduction for smokers living with HIV. The Lancet HIV. 2021; 8(10): E652-E658.</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">【7】Reddy KP, et al. Lung Cancer Mortality Associated With Smoking and Smoking Cessation Among People Living With HIV in the United States. JAMA Intern Med. 2017;177(11):1613–1621.</span><a style="color: black;"><span style="color: black;">返回<span style="color: black;">外链论坛:http://www.fok120.com/</span>,查看<span style="color: black;">更加多</span></span></a></p>
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