要去开刀的“肺癌”病人,其实是“霉雨”过敏
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPlwdk4Z0YgM0Ppy4A6gUSceR4yFP5Ngo8pAqeiclm1SRPYk1Nkys1ypA/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">下午四点,方家的餐桌上<span style="color: black;">已然</span>琳琅满目香气袭人:</span><span style="color: black;">油焖笋、酒香草头、糖醋排骨、油爆河虾……今天是儿子小方放暑假从北京回来的日子,老方两口子<span style="color: black;">已然</span>准备多时了。</span><span style="color: black;">在老方第五次去阳台张望的时候,小方的身影<span style="color: black;">最终</span>出<span style="color: black;">此刻</span>了楼下。</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPQlMxBE6ib4qL4waF1EDWDNt2cxtYyFu03jNt65FesqqnvGLYwMh9mYA/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">半年未见,老方一边卸下儿子的行李,一边问个<span style="color: black;">一直</span>:</span><span style="color: black;">——“北方夏天热不热呀?”</span><span style="color: black;">——“不热,<span style="color: black;">重要</span>是不会<span style="color: black;">始终</span>下雨。”</span><span style="color: black;">——“和室友相处得好<span style="color: black;">欠好</span>呀?”</span><span style="color: black;">——“挺好的,有一个还是‘吃鸡’大神,<span style="color: black;">尤其</span>厉害。”</span><span style="color: black;">——“考试考得……咳咳……怎么样……”</span><span style="color: black;">——“爸你肺炎又犯病啦?我考试还行吧,期末这两周都没打游戏。”</span><span style="color: black;">老方还想问点什么,<span style="color: black;">然则</span>感觉咳嗽有点停不下来,他不想扫一家人的兴,强忍着咳嗽去了卫生间。不一会,<span style="color: black;">无</span>间隙的咳嗽声似乎要从卫生间溢出来了。</span><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPvHticNgOn44j8b5y8FnIqD3EZy2c3LVianSVImLq7XAiaIOPaJSDS17Eg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">过了一会,老伴进来了。“你这都咳嗽一个来月了,还越来越重,还是去<span style="color: black;">瞧瞧</span>吧。”</span><span style="color: black;">“都是老支扩(支气管扩张)了,我的身体我心里有数。”老张咳得脸通红,还是不忘嘴硬。</span><span style="color: black;">“以前不都是冬天咳嗽,夏天哪有这么厉害过?!”</span><span style="color: black;">老方不说话了,老伴点破了他的心事。</span><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;"><span style="color: black;">次日</span>一早,老方两口子给儿子留了字条说去逛公园,出门去了医院——小方前一晚打游戏到深夜,还没起床。</span><span style="color: black;">接诊的是个<span style="color: black;">青年</span><span style="color: black;">大夫</span>,听诊器一搭,“有啰音,做个肺CT<span style="color: black;">瞧瞧</span>吧。”</span><span style="color: black;"><span style="color: black;">火速</span>CT做好了,<span style="color: black;">大夫</span>翻来覆去看了好几遍片子,眉头越皱越紧。</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPPAnGDD7Soppyia6nUFuRLgxqYsFlDq64y9buBhb9McZkPfebicfhaWLA/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">——“吸烟吗?有咯血吗?<span style="color: black;">近期</span>体重有下降吗?”</span><span style="color: black;">——“不吸,我这老支扩,<span style="color: black;">大夫</span>不让吸;以前有痰中带血,<span style="color: black;">近期</span>一两年都<span style="color: black;">无</span>过;体重嘛,<span style="color: black;">近期</span>可能比较累,忙着给我儿子翻修房间,瘦了两三斤。”老方答到,末了还不忘自豪地<span style="color: black;">弥补</span>一句:“我儿子上大学,暑假回家了。”</span><span style="color: black;">——“<span style="color: black;">这般</span>吧,你先查个血,查完就先回家,<span style="color: black;">夜晚</span>在手机app上看结果。”没等老方再问,<span style="color: black;">大夫</span>像是<span style="color: black;">晓得</span>他要说什么,挥挥手说:“先查吧,片子得结合验血看,<span style="color: black;">此刻</span>还<span style="color: black;">欠好</span>下结论。”</span><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">老方心里隐隐觉得不太对,以前他支气管扩张看<span style="color: black;">大夫</span>的时候,<span style="color: black;">大夫</span>都很爽快地直接跟他说病情的。回家吃完饭,老方让老伴先出门去广场舞场地占位置,老伴一出门,他赶紧掏出手机查验血结果。</span><span style="color: black;">一个红色的指标印入眼帘:癌胚抗原(CEA) 28.8ng/ml(正常<5ng/ml),<span style="color: black;">上升</span>。</span><span style="color: black;">老方瞬间坐正了,看到“癌”这个字,他心里有些发慌。百度一下,清一色地说这是个癌症指标,跟结肠癌、胃癌、肺癌等等肿瘤关系密切,越是晚期越高……等等,什么?肺癌?</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPZuo9hNbU4MhxsvEL2k5qXemdblYdlDKoYMc7Lj0mBBcqKcOqSUKESg/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">怪不得<span style="color: black;">大夫</span>看了肺CT之后眉头紧皱,还问有<span style="color: black;">无</span>体重下降,难不成<span style="color: black;">大夫</span><span style="color: black;">可疑</span>……?!可是<span style="color: black;">孩儿</span>还打算申请出国,父母都80多岁了,正是到处都要用钱的时候……老方不敢想下去了。他<span style="color: black;">忽然</span>想起自己有个<span style="color: black;">伴侣</span><span style="color: black;">好似</span>是个外科<span style="color: black;">大夫</span>,赶紧把指标截屏发给他问问<span style="color: black;">状况</span>。<span style="color: black;">大夫</span><span style="color: black;">伴侣</span>大概还在忙,<span style="color: black;">无</span>马上回复,等待中的老方坐立不安,不敢想,又忍不住乱想。</span><span style="color: black;">“叮”,手机响了一下,老方一秒钟都没耽搁看向手机:“这指标高了好几倍,要高度<span style="color: black;">可疑</span>肿瘤,是你什么人呀?<span style="color: black;">近期</span>有哪里不舒服?这个得赶紧住院好好查一查,查清楚能开刀就趁早开刀。”老方看完,心都凉了。</span><span style="color: black;">——“快来!那里有人!”“空投落了,追啊!”儿子打游戏的声音传出来。老方愣了一会,进了他的房间。</span><span style="color: black;">——“儿子,少打点游戏吧。”</span><span style="color: black;">——“嗯。”小方嘴上应着,头<span style="color: black;">亦</span>没抬。</span><span style="color: black;">——“儿子,你妈脾气不太好,以后你让着她点。她血压<span style="color: black;">亦</span>高,你以后打<span style="color: black;">tel</span>都提醒着点她按时吃药。”</span><span style="color: black;">——“我刚回来一天,又没惹她……我被98K爆了,快来扶我一下!”</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPXv6mW2ygibnDgT0VXKtWkGEIDoA9SEKrHmbZX7LhnyjDHgjUdDfQPHQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">老方轻轻叹了口气,走出了房间。</span><span style="color: black;"><span style="color: black;">此时</span>老伴回来了,“等你半天你<span style="color: black;">亦</span>没去,验血结果怎么样”,方叔有些支吾地说“啊,都挺好,挺正常的” ,他还<span style="color: black;">无</span>想好怎么说,怕吓到她。“真好假好,你别瞒着我呀!”“怎么这么啰嗦,好<span style="color: black;">便是</span>好呀,箭头我还不会看了?快洗澡睡觉吧,今天折腾了一天,有点累了。”方叔定了定神,口气斩钉截铁。</span><span style="color: black;">这一晚,老方翻来覆去睡不着,一半<span style="color: black;">由于</span>咳嗽,一半<span style="color: black;">由于</span>担心,老伴以后身体<span style="color: black;">欠好</span>怎么办,儿子可什么时候<span style="color: black;">才可</span><span style="color: black;">成长</span>啊……</span><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">老方咳了一<span style="color: black;">夜晚</span>,老伴还是不<span style="color: black;">安心</span>,一大早起来就拉着他再去医院,方叔不愿去却又拗<span style="color: black;">不外</span>。</span><span style="color: black;">诊室里,<span style="color: black;">大夫</span>面色凝重,问方婶“你是他爱人?”方婶点点头。<span style="color: black;">大夫</span>转头对老方说:“有些报告还没出全,你去检验科问一下几点能出吧” 。</span><span style="color: black;">老方一下子心领神会:“<span style="color: black;">大夫</span>您<span style="color: black;">不消</span>瞒我,我有个癌症指标很高,<span style="color: black;">是否</span>不太好,您直说就行” 。方婶<span style="color: black;">满脸</span>惊讶地<span style="color: black;">瞧瞧</span>老方,又赶紧转过来<span style="color: black;">瞧瞧</span><span style="color: black;">大夫</span>。</span><span style="color: black;"><span style="color: black;">大夫</span>语调低沉:“CT上看到右上肺有块肿块,倒是很光滑,<span style="color: black;">然则</span>旁边<span style="color: black;">非常多</span>血管,<span style="color: black;">周边</span>还有些大病灶……血里查出来癌胚抗原很高,<span style="color: black;">通常</span>我们认为跟肿瘤<span style="color: black;">相关</span>,<span style="color: black;">特别有</span>可能是个肺腺癌,<span style="color: black;">必须</span>尽早开刀,<span style="color: black;">意见</span>尽早住院吧” 。</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXP5ibWyIMAGgia1VGJiaRUVDjtHYkPAOWLhhYXkia5bXhzC8t88UefDOyAeA/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">张婶一下子懵了,<span style="color: black;">心情</span>激动起来:“这怎么可能,不会搞错了吧!去年体检还<span style="color: black;">仅有</span>支扩!哎呀其实<span style="color: black;">已然</span>咳嗽一个来月了,早点来看就好了……”</span><span style="color: black;">”<span style="color: black;">这般</span>吧,要不您再去看一下中山医院感<span style="color: black;">患病</span>科的胡必杰教授,他尤其是看疑难肺部<span style="color: black;">疾患</span>很厉害,请他再<span style="color: black;">瞧瞧</span>像什么,必要的话做个病理活检<span style="color: black;">知道</span>一下,<span style="color: black;">而后</span>再说后面的事。“<span style="color: black;">青年</span><span style="color: black;">大夫</span><span style="color: black;">弥补</span>说到。</span><span style="color: black;">老方心里明白,<span style="color: black;">大夫</span>这是怕自己和家人接受不了,用了个缓兵之计罢了。老伴却像是抓住了救命稻草:“对对,老方你听到了吗,<span style="color: black;">大夫</span>说让先<span style="color: black;">知道</span>下,你别急。” 这话是她对着老方说的,又像是对自己说的。</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXP2md9hshAMRia3SSnmJCty7SfKoj1Fiaeiaq84htmwy6eInywQrkpTw7dg/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">回到家,儿子<span style="color: black;">已然</span>起床了。老方去卫生间洗手的时候,小方<span style="color: black;">亦</span>跟了进去:“爸,你们去哪了?” “没去哪,就逛逛公园。”老方答到。“我看到你手机定位了,你们这两天都去医院了。爸你昨天<span style="color: black;">夜晚</span>跟我说那话是什么意思?”老方心里一下子宽慰了<span style="color: black;">有些</span>,故作<span style="color: black;">容易</span>地说:“没事的,还是咳嗽的老毛病,<span style="color: black;">大夫</span>说得再<span style="color: black;">检测</span><span style="color: black;">检测</span>。”</span><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">小方给父亲预约了中山医院胡必杰教授的门诊。门诊楼里,儿子一手拿着雨伞和病历资料,另一手拉着老方的手臂张罗着挂号、签到、找诊室,又不时地回头关照父母小心地滑。老方跟在后面,心里想,时间要是停在<span style="color: black;">此时</span>候,该有多好。</span><span style="color: black;">——“胡教授,我爸<span style="color: black;">近期</span>咳嗽,肺CT报告说长东西了,验血有个肿瘤指标<span style="color: black;">亦</span>高。之前看<span style="color: black;">大夫</span>,说肺里的东西像是<span style="color: black;">欠好</span>的那种,要开刀,他以前有支气管扩张,<span style="color: black;">不外</span><span style="color: black;">始终</span>都挺稳定的。您给<span style="color: black;">瞧瞧</span>。”到底是<span style="color: black;">青年</span>人,小方说话简明扼要,直抓重点。</span><span style="color: black;">——“好的,有痰吗?有咯血吗?”胡教授问。</span><span style="color: black;">——“我是老支扩,<span style="color: black;">始终</span>都有痰的;血以前咯过,<span style="color: black;">近期</span><span style="color: black;">无</span>。”老方答到。</span><span style="color: black;">——“痰什么颜色?”</span><span style="color: black;">——“以前是黄脓痰,<span style="color: black;">近期</span>有点发黑,还蛮多的,经常是一大块一大块的。”老方一五一十地回答。</span><span style="color: black;">——“大块的痰?那有<span style="color: black;">无</span>那种像橡胶手套<span style="color: black;">同样</span>分叉又“有型”的痰?”胡教授语调高了<span style="color: black;">有些</span>。</span><span style="color: black;">——“这个……哎<span style="color: black;">好似</span>是有一次咳出来分叉的,我当是吃的东西不小心呛进去了,没<span style="color: black;">留意</span>。”</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXP02I0XCk5lSLMwRdpAd3IW09WQwib3Ua3U0AVicbTY3IE8wOzQJZVIAXw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">——“那<span style="color: black;">近期</span>有<span style="color: black;">无</span>接触发霉的东西呢?“</span><span style="color: black;">——“没有<span style="color: black;">无</span>,家里吃的东西都<span style="color: black;">鲜嫩</span>的,<span style="color: black;">无</span>发霉的。”老方的口气非常肯定。</span><span style="color: black;">——“像报纸、书、皮鞋、墙皮、下水道之类,有<span style="color: black;">无</span>发霉的?”胡教授追问。</span><span style="color: black;">——“前段时间你不是在给儿子翻修房间,那房间都半年没人动了,有<span style="color: black;">无</span>什么发霉的?”老伴提醒老方。</span><span style="color: black;">——“啊对!今年梅雨厉害,是有书发了霉,这应该没啥影响吧?我儿子暑假回来之前,我想给他房间理一理,黑色的痰我觉得可能是<span style="color: black;">由于</span>房间里的灰尘。”被老伴这么一提醒,老方叔赶紧<span style="color: black;">弥补</span>了一下。</span><span style="color: black;">——“这可影响大了!”胡教授笑笑:“那就对了,你这CT上病灶比较圆,边界比较光滑,靠近中心,又是在接触发霉物品后<span style="color: black;">显现</span>的症状,有可能是霉菌过敏。”</span><span style="color: black;">——“不是癌症?!”老方仔细回想了下,他的咳嗽咳痰,<span style="color: black;">好似</span>确实是从<span style="color: black;">起始</span>整理房间起加重的,瞬间感觉天都晴了,</span><span style="color: black;">——“胡教授,<span style="color: black;">咱们</span>有个肿瘤指标很高很高,都说是肿瘤,您看呐?”方婶<span style="color: black;">弥补</span>问道</span><span style="color: black;">——“我看到了,<span style="color: black;">一般</span><span style="color: black;">状况</span>下这两者是紧密<span style="color: black;">关联</span>的,<span style="color: black;">然则</span>霉菌过敏的时候这个指标<span style="color: black;">亦</span><span style="color: black;">能够</span><span style="color: black;">上升</span>,<span style="color: black;">必须</span>仔细鉴别一下”。</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXP42ChKuT9icuqCQOZltftVaedc1mM6kT95umIlqPKMuHMicHr0z1tbjeQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">听了胡教授的解释,一家三口都长舒了一口气。在胡教授的<span style="color: black;">意见</span>之下,老方办理了住院。</span><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">入院后</span><span style="color: black;">的验血中,<span style="color: black;">大夫</span><span style="color: black;">发掘</span>老方的嗜酸性粒细胞和IgE<span style="color: black;">显著</span><span style="color: black;">上升</span>,尤其是曲霉特异性IgE<span style="color: black;">显著</span><span style="color: black;">上升</span>。</span><span style="color: black;">胡教授给<span style="color: black;">大众</span>讲解说:</span><span style="color: black;">“这个病人的影像学不是太典型,猛一看像肿瘤,但仔细看边缘太光滑了。</span><span style="color: black;">”</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">“<span style="color: black;">咱们</span><span style="color: black;">另一</span>找一个上周我看过的典型的ABPA(过敏性支气管肺曲霉菌病)<span style="color: black;">病人</span>的CT看(padapada电脑调出来),非常有特点,你们看这个支气管,像不像示指和中指在比“耶”的姿势?”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPxghJia60Ekib6obouMlZaDHf5CtXbIIgA4HPL84lQxC8PjIhtscTYsDw/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">住院<span style="color: black;">大夫</span>们看后纷纷点头,想笑又都有些不好意思。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">“这些病人,是<span style="color: black;">因为</span>人吸入曲霉菌后,对曲霉抗原<span style="color: black;">出现</span>变态反应,<span style="color: black;">引起</span>支气管黏膜产生炎症、坏死;支气管的粘液分泌<span style="color: black;">反常</span>、<span style="color: black;">然则</span>又排不出去,就在支气管腔内积聚、结块,就形<span style="color: black;">成为了</span><span style="color: black;">咱们</span>在CT上看到的手指头<span style="color: black;">同样</span>的征象。<span style="color: black;">少许</span>病灶,个头长的<span style="color: black;">尤其</span>大,不仔细分析会误认为肿瘤的,就像<span style="color: black;">咱们</span>这个病人。</span><span style="color: black;">有人</span><span style="color: black;"><span style="color: black;">乃至</span>被开了冤枉刀。</span><span style="color: black;">而</span><span style="color: black;">成块的粘液<span style="color: black;">倘若</span></span><span style="color: black;">偶然被病人咳出体外,<span style="color: black;">便是</span>橡胶手套形状的痰</span><span style="color: black;">。</span><span style="color: black;">”</span></p><span style="color: black;">“这个病本质是曲霉过敏。南方比较温暖潮湿,尤其是梅雨季节湿度更大,霉菌容易生长,<span style="color: black;">引起</span>墙皮发黑、下水道散发霉味之类,<span style="color: black;">海量</span>曲霉<span style="color: black;">胞子</span>被人吸入后就容易<span style="color: black;">显现</span>这个病。”胡教授<span style="color: black;">仔细</span>讲解到。</span><span style="color: black;">“<span style="color: black;">日前</span>他的血嗜酸性粒细胞<span style="color: black;">上升</span>、曲霉特异性IgE<span style="color: black;">上升</span>,都指向ABPA这个<span style="color: black;">疾患</span>。接下来<span style="color: black;">咱们</span><span style="color: black;">必须</span>做个气管镜,取标本做病原病理学<span style="color: black;">检测</span>加以<span style="color: black;">知道</span>,还<span style="color: black;">能够</span>进一步排除肿瘤。”</span><span style="color: black;">末了,胡教授又<span style="color: black;">弥补</span>到:“说来有意思,癌胚抗原<span style="color: black;">通常</span><span style="color: black;">来讲</span>是比较特异的肿瘤指标,但这几年<span style="color: black;">咱们</span>收治了百来例ABPA的<span style="color: black;">病人</span>,<span style="color: black;">发掘</span>有些<span style="color: black;">病人</span>癌胚抗原<span style="color: black;">亦</span>会<span style="color: black;">上升</span>,<span style="color: black;">常常</span>被误诊为肿瘤开刀,其实抗ABPA治疗后,<span style="color: black;">她们</span>的癌胚抗原会快速下降。<span style="color: black;">大众</span>后续<span style="color: black;">能够</span>关注下这个病人验证下。”</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPicBgrGZ2IaHt7kta63w1JchMPInbHdfdtNyIb75ykpB3xzENejUr5oQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">各项<span style="color: black;">检测</span>紧锣密鼓地安排起来,又<span style="color: black;">持续</span><span style="color: black;">报答</span>喜讯:痰真菌培养:曲霉属1+;气管镜下看到了管腔痰栓嵌塞;肺组织病理未见肿瘤依据……个个都指向ABPA这个<span style="color: black;">疾患</span>。<span style="color: black;">大夫</span><span style="color: black;">思虑</span>ABPA诊断<span style="color: black;">知道</span>,<span style="color: black;">第1</span>时间给老方用上了针对性的<span style="color: black;">药品</span>。</span><span style="color: black;">老方一家听说不是肿瘤非常开心,用药后老方的咳嗽咳痰都有<span style="color: black;">显著</span>的好转,之前<span style="color: black;">上升</span>的嗜酸性粒细胞、IgE都降下来了,最让<span style="color: black;">她们</span>牵挂的肿瘤指标——癌胚抗原<span style="color: black;">亦</span>大幅度下降。2周后,<span style="color: black;">大夫</span>给老方复查了肺部CT,肿块不见了,变<span style="color: black;">成为了</span>空心的扩张的支气管腔。老方一家心中的石头总算落了地。</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXPX4hpX55KPaKbS4pPiagHXX2w0jHwaPZaAZ7EGvZrtZWWYLpicySyr7wg/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">经此一事,老方对戴口罩和监督家人戴口罩越发上心;而小方得知父亲是给他整理房间才<span style="color: black;">患病</span>之后,心里又是愧疚又是后怕,为了不让父母操心,游戏<span style="color: black;">亦</span>不打了——虽然被室友<span style="color: black;">抱怨</span>,小方对父亲的病却绝口不提;老方老两口虽然不知这些细节,却<span style="color: black;">亦</span><span style="color: black;">显著</span>觉得儿子是个能“扛住事”的<span style="color: black;">成人</span>了。</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/t5El0TaoUM4V7H7oSribw1D3WeEZHiblXP69tD1CqBFGaNRmhicKPWtTqtFnawBsXBcCNpESVY0ia0fR2BMLQfEUHQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><img src="https://mmbiz.qpic.cn/mmbiz_png/uns8embQaqskVQCLTiaRBaQRvEOctRbuQGq7UZW7z4jR6ON4KlhO37TPkFlQoicr2QIXTffLiatAGYwEoE2icicIwEQ/640?wx_fmt=png&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><img src="https://mmbiz.qpic.cn/mmbiz_gif/tjMytVfPsjBu6QJAicoL32RsDpO6S1JvFUJiabKDgR52aibI8bZPvGmgGwmYbWd9VXN2JFicLBBXUdFbRBiarG5PiclA/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">关联</span>案例</p><img src="https://mmbiz.qpic.cn/mmbiz_gif/LianbibNTn3Ns455IPTPVwfkoibGedrmpxn8FnwlbKLur87Z6HRrjYicNN8lhdgzTEPiak9AYO5HslVhvNXicKAgWeGA/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;">来自东北的王帅<span style="color: black;">始终</span>身强体壮,<span style="color: black;">近期</span>一年却反复咳嗽气喘。起初<span style="color: black;">大夫</span><span style="color: black;">思虑</span>哮喘,用了药好了一段时间之后又加重了,CT还<span style="color: black;">发掘</span>了肺部病灶,肿瘤标志物中的癌胚抗原高达60ng/ml。<span style="color: black;">各样</span>高级抗菌<span style="color: black;">药品</span>用了个遍,肺里的病灶反而还变大变多了。眼看儿子被<span style="color: black;">疾患</span><span style="color: black;">熬煎</span>得郁郁寡欢,王帅的父母焦急万分。打听到上海的胡必杰教授诊治疑难杂症的水平很高,一家人从东北飞到上海求医。胡教授仔细翻看了小王的验血报告、CT,<span style="color: black;">仔细</span>询问了病史,门诊即诊断他ABPA。规律用药后,王帅的症状<span style="color: black;">快速</span>好转,肺部病灶<span style="color: black;">亦</span>消失了。<img src="https://mmbiz.qpic.cn/mmbiz_gif/LianbibNTn3Ns455IPTPVwfkoibGedrmpxn8FnwlbKLur87Z6HRrjYicNN8lhdgzTEPiak9AYO5HslVhvNXicKAgWeGA/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;">徐阿姨从小在上海<span style="color: black;">成长</span>,平时的工作是看管和整理仓库。上海雨多,装货的木箱发霉是常事,赶上梅雨,<span style="color: black;">全部</span>仓库里都弥漫着霉味。徐阿姨有点支气管扩张,是老毛病了,<span style="color: black;">始终</span>都还算稳定,<span style="color: black;">然则</span><span style="color: black;">近期</span>一段时间她总觉得<span style="color: black;">呼气</span>不顺畅,咳嗽止不住,还总咳出褐色的痰。辗转找到中山医院感<span style="color: black;">患病</span>科,胡教授一看CT便<span style="color: black;">思虑</span>可能是曲霉过敏<span style="color: black;">导致</span>的ABPA,便问她有<span style="color: black;">无</span>接触霉变的东西。徐阿姨一下子打开了话匣子:梅雨季,木头发霉天天见,这还会<span style="color: black;">患病</span>呐?哎你还别说,每年大约梅雨这个时候,总归觉得肺里不舒服,总得住几天医院!徐阿姨恍然大悟,她决定每年梅雨季节时离开上海,去干燥的北方城市,她的ABPA果然没再复发过。<img src="https://mmbiz.qpic.cn/mmbiz_gif/tjMytVfPsjBu6QJAicoL32RsDpO6S1JvFUJiabKDgR52aibI8bZPvGmgGwmYbWd9VXN2JFicLBBXUdFbRBiarG5PiclA/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">大夫</span>提醒</p><img src="https://mmbiz.qpic.cn/mmbiz_gif/LianbibNTn3Ns455IPTPVwfkoibGedrmpxn8FnwlbKLur87Z6HRrjYicNN8lhdgzTEPiak9AYO5HslVhvNXicKAgWeGA/640?wx_fmt=gif&tp=webp&wxfrom=5&wx_lazy=1" style="width: 50%; margin-bottom: 20px;"><strong style="color: blue;">1、</strong><strong style="color: blue;">ABPA预防大于治疗:接触发霉物品,<span style="color: black;">意见</span>佩戴N95口罩!</strong>曲霉在<span style="color: black;">平常</span>生活中很<span style="color: black;">平常</span>,尤其是潮湿、湿热的环境中,<span style="color: black;">例如</span>老旧的墙壁、发霉的皮具、腐烂的稻草堆等。其生长繁殖时会产生<span style="color: black;">海量</span>分生<span style="color: black;">胞子</span>。<span style="color: black;">胞子</span>很轻,可在空气中漂浮很<span style="color: black;">长期</span>,很容易被人吸入肺里。环境或物品有<span style="color: black;">显著</span>霉味或发霉表现、而又<span style="color: black;">必要</span>接触时,建议开窗通风,全程佩戴N95口罩。N95口罩可有效滤过<span style="color: black;">胞子</span>,减少接触,减少ABPA复发或加重的机会。<strong style="color: blue;">2、</strong><strong style="color: blue;">顽固性哮喘<span style="color: black;">病人</span>需<span style="color: black;">警觉</span>ABPA</strong><span style="color: black;">一般</span>,哮喘<span style="color: black;">病人</span>的CT上<span style="color: black;">无</span><span style="color: black;">显著</span>的肺部病灶。但部分<span style="color: black;">病人</span>难以<span style="color: black;">掌控</span>、疗效欠佳、反复<span style="color: black;">爆发</span>,尤其CT<span style="color: black;">表示</span>肺内有病灶者需<span style="color: black;">警觉</span>ABPA。<strong style="color: blue;">3、ABPA治疗时间长,可能会复发,<span style="color: black;">必须</span><span style="color: black;">长时间</span>随访</strong>ABPA治疗时间较长<span style="color: black;"></span>,糖皮质激素<span style="color: black;">必须</span>遵从医嘱<span style="color: black;">调节</span>剂量,否则容易<span style="color: black;">显现</span>病情复发或反跳。病人<span style="color: black;">一般</span><span style="color: black;">必须</span><span style="color: black;">定时</span><span style="color: black;">长时间</span>门诊随访,治疗要有耐心。<span style="color: black;">另一</span>,<span style="color: black;">长时间</span><span style="color: black;">吃下</span>激素抵抗力下降,且伴有支气管扩张,容易合并其他细菌感染如铜绿假单胞菌、非结核分枝杆菌等等,<span style="color: black;">因此呢</span>,<span style="color: black;">倘若</span>黄痰<span style="color: black;">增加</span>或<span style="color: black;">显现</span>发热时,要<span style="color: black;">即时</span>就诊。<span style="color: black;"></span><span style="color: black;"></span><strong style="color: blue;">4、部分ABPA<span style="color: black;">病人</span>的癌胚抗原(CEA)<span style="color: black;">能够</span><span style="color: black;">显著</span><span style="color: black;">上升</span></strong>CEA是胃癌、肠癌和肺癌等恶性肿瘤的<span style="color: black;">要紧</span>筛查标志物。值得指出的是,部分ABPA<span style="color: black;">病人</span>,其CEA<span style="color: black;">亦</span><span style="color: black;">能够</span><span style="color: black;">显著</span><span style="color: black;">上升</span>。但随着糖皮质激素治疗、ABPA病情的改善,CEA<span style="color: black;">能够</span><span style="color: black;">逐步</span>下降。<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">作者:马玉燕</span><span style="color: black;"> 黄英男</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">审核:胡必杰 潘珏</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">图文整理:陈小小 黄英男</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">往期精品<span style="color: black;">举荐</span></strong></span></p><a style="color: black;"><span style="color: black;">第26期丨“铁手何”阅鱼<span style="color: black;">没</span></span></a>数,一根刺让他遭遇滑铁卢<a style="color: black;">第25期丨前年的一只三黄鸡,在今年险些要了他的命</a><a style="color: black;">第24期丨美国加州“杀人”事件</a><a style="color: black;">第23期丨这一年他千疮百孔,却又迎来了重生</a><a style="color: black;">第22期丨十年咯血,<span style="color: black;">最终</span>有人对她说:确诊了,你的肺结节是良性的</a><a style="color: black;"><span style="color: black;">第21期丨一次游泳开启的潘多拉魔盒</span></a><a style="color: black;">第20期丨一只脚踩进鬼门关的“关系户”</a><a style="color: black;">第19期丨一个<span style="color: black;">大夫</span>被狗</a>咬伤后的一百个日夜<a style="color: black;">第18期丨“鸡娃”二十<span style="color: black;">数年</span>,藤校“牛蛙”妈妈总结出一个结论</a><a style="color: black;"><span style="color: black;">第17期丨掩盖在红裙之下的三十处伤口</span></a><a style="color: black;">第16期丨困在发烧漩涡里的中年健美先生</a><a style="color: black;">第15期丨四起四伏,发烧半年只因一盘菜</a><a style="color: black;">第14期丨血溅木雕,他能否逃出山神的诅咒?</a><a style="color: black;"><span style="color: black;">第13期丨夜半的“血”案,谜底藏在荒废已久的阁楼里</span></a><a style="color: black;">第12期丨一个蹊跷的</a>脓肿,和一对父子在生死面前的默契<a style="color: black;">第11期丨“伤心”“动骨”又“犯肺”,原来竟是“祸从口出” ——盘点<span style="color: black;">哪些</span>口腔细菌惹的祸</a><a style="color: black;">第10期丨肺里有牛奶?还可能有<span style="color: black;">月经</span>?你<span style="color: black;">是否</span>小看肺炎了</a><a style="color: black;">第9期丨我的尿路感染<span style="color: black;">为何</span>总<span style="color: black;">亦</span>好不了?</a><a style="color: black;">第8期丨医学美容<span style="color: black;">暗地里</span>的感染陷阱</a><a style="color: black;">第7期丨既要防扩散,又要防感染!——癌症病人<span style="color: black;">尤其</span><span style="color: black;">必须</span>预防的</a>10种感染<a style="color: black;">第6期丨健康铲屎指南之其他动物篇</a><a style="color: black;">第5期丨我摸到淋巴结,是不祥之兆吗?</a><a style="color: black;">第4期丨吸猫撸狗欲罢<span style="color: black;">不可</span>,你<span style="color: black;">必须</span><span style="color: black;">这般</span>一份健康铲屎指南</a><a style="color: black;">第3期丨肺炎-这世界上最凶的“杀手”,请吃我20拳!!</a><a style="color: black;">第2期丨刀下留肺!——容易误认为癌性“肺结节”的8种感染</a><a style="color: black;">第1期丨学会这十招,感染远离你!</a><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;">
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">上海中山医院感<span style="color: black;">患病</span>科</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">高级专家、普通和专病门诊时间</span></p><span style="color: black;">高级专家门诊(东院区:斜土路1609号)</span><span style="color: black;">胡必杰教授:周一下午、周三上午、周四上午</span><span style="color: black;">潘珏<span style="color: black;">专家</span>医师:周二下午、周四下午、周五上午</span><span style="color: black;">感<span style="color: black;">患病</span>科普通门诊(西院区:医学院路111号)</span><span style="color: black;">周一至周六全天</span><span style="color: black;">肺外结核专病门诊(西院区:医学院路111号)</span><span style="color: black;">周<span style="color: black;">1、</span>周<span style="color: black;">3、</span>周五下午</span><span style="color: black;">真菌感染专病门诊(西院区:医学院路111号)</span><span style="color: black;">周<span style="color: black;">1、</span>四上午</span><span style="color: black;">淋巴结肿大专病门诊(西院区:医学院路111号)</span><span style="color: black;">周二上午、周四下午</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">医学美容感染专病门诊(西院区:医学院路111号</span>)</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"> • </span><span style="color: black;"> 周三上午、周六上午</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">T-SPOT<span style="color: black;">上升</span>门诊<span style="color: black;">(西院区:医学院路111号)</span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"> • </span>周二下午、周五上午</span></p>
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