癌症-科研丨专家给多种癌症供给致命打击
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">点击上方<span style="color: black;">“蓝色字体”</span>可订阅哦！</p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">按照</span>英国“癌症<span style="color: black;">科研</span>”（Cancer Research UK）<span style="color: black;">帮助</span>的<span style="color: black;">科研</span>报告，<span style="color: black;">日前</span>靶向已被癌细胞劫持的健康细胞<span style="color: black;">能够</span>治疗许多不同类型的<span style="color: black;">疾患</span>，今天<span style="color: black;">发布</span>在“国家癌症<span style="color: black;">科研</span>协会杂志”上。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">专家</span><span style="color: black;">发掘</span>，靶向<span style="color: black;">叫作</span>为NOX4的酶会阻止<span style="color: black;">叫作</span>为癌症<span style="color: black;">关联</span>成纤维细胞（CAFs）的细胞类型的<span style="color: black;">功效</span>，将小鼠肿瘤的<span style="color: black;">体积</span>减少高达50％。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">成纤维细胞是健康细胞，其<span style="color: black;">功效</span>是将不同类型的器官保持在<span style="color: black;">一块</span>。当它们被癌细胞劫持时，它们<span style="color: black;">作为</span>CAF，已知<span style="color: black;">能够</span><span style="color: black;">帮忙</span>肿瘤生长，扩散和逃避治疗。到<span style="color: black;">日前</span>为止，试图针对<span style="color: black;">她们</span><span style="color: black;">已然</span>证明是不成功的做法。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">按照</span>以前的<span style="color: black;">科研</span>，南安普敦大学的<span style="color: black;">科研</span>小组<span style="color: black;">发掘</span>，较高水平的CAF与几种癌症（<span style="color: black;">包含</span>肠，头颈部癌症）的<span style="color: black;">存活</span>率较差<span style="color: black;">相关</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">她们</span>首次<span style="color: black;">发掘</span>，CAF<span style="color: black;">必须</span><span style="color: black;">运用</span>NOX4来形成并<span style="color: black;">帮忙</span>许多癌症类型的肿瘤生长。<span style="color: black;">然则</span><span style="color: black;">她们</span><span style="color: black;">能够</span><span style="color: black;">经过</span>阻止NOX4<span style="color: black;">运用</span>被<span style="color: black;">研发</span>用于治疗<span style="color: black;">叫作</span>为器官纤维化的病症的<span style="color: black;">药品</span>来阻止这种<span style="color: black;">状况</span><span style="color: black;">出现</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">这些<span style="color: black;">发掘</span><span style="color: black;">能够</span>形成新治疗的<span style="color: black;">基本</span>，并<span style="color: black;">帮忙</span>癌症对现有<span style="color: black;">药品</span>做出更好的反应。英国癌症<span style="color: black;">科研</span><span style="color: black;">分部</span><span style="color: black;">此刻</span><span style="color: black;">帮助</span>南安普敦的<span style="color: black;">专家</span>，<span style="color: black;">瞧瞧</span>这种方法<span style="color: black;">可否</span>改善了治疗<span style="color: black;">办法</span>，如免疫治疗和化学疗法，使其更有效。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">南安普敦大学实验病理学<span style="color: black;">专家</span><span style="color: black;">科研</span>员兼首席<span style="color: black;">科研</span>员Gareth Thomas教授说：“<span style="color: black;">经过</span>观察许多类型的癌症，<span style="color: black;">咱们</span><span style="color: black;">已然</span>确定了CAF在肿瘤中形成的<span style="color: black;">平常</span>机制。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">“这些细胞使癌症<span style="color: black;">拥有</span>攻击性，难以治疗，<span style="color: black;">咱们</span><span style="color: black;">能够</span>看到令人兴奋的可能性，针对CAF在许多<span style="color: black;">病人</span>对现有治疗效果<span style="color: black;">不良</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">英国癌症<span style="color: black;">科研</span>部高级科学信息官áineMcCarthy博士说：“<span style="color: black;">有些</span>癌症难以治疗，<span style="color: black;">能够</span><span style="color: black;">运用</span>身体<span style="color: black;">自己</span>的细胞来<span style="color: black;">帮忙</span><span style="color: black;">她们</span>成长，逃避治疗和传播到身体<span style="color: black;">周边</span>。<span style="color: black;">科研</span>人员<span style="color: black;">始终</span>试图解锁这个<span style="color: black;">科研</span><span style="color: black;">数年</span>来的<span style="color: black;">奥密</span>，这项<span style="color: black;">科研</span>是<span style="color: black;">认识</span><span style="color: black;">有些</span>癌症<span style="color: black;">怎样</span>实现这一<span style="color: black;">目的</span>的一大进步。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">“这些<span style="color: black;">科研</span>结果<span style="color: black;">显示</span>，CAF<span style="color: black;">能够</span>针对一种<span style="color: black;">药品</span>，<span style="color: black;">她们</span>的”前肿瘤“效应<span style="color: black;">能够</span>在小鼠中逆转，从而使<span style="color: black;">科研</span>人员<span style="color: black;">作为</span><span style="color: black;">将来</span><span style="color: black;">研发</span>新的和潜在的更有效的治疗<span style="color: black;">办法</span>的出发点。"</p>
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