专家视角：基因检测彻底改变癌症诊断、治疗！
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">因为</span>基因检测技术的进步，专家<span style="color: black;">此刻</span><span style="color: black;">能够</span>分析数百个基因，而过去只能分析几个基因，这使得专家<span style="color: black;">能够</span>更快、更有效地为<span style="color: black;">每一个</span>癌症<span style="color: black;">病人</span>制定正确的治疗<span style="color: black;">办法</span>。</span></p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">2024年3月28日，David Bartlett博士接受《Targeted Oncology》杂志采访，讨论了基因检测在癌症治疗中的应用及其日益增长的<span style="color: black;">要紧</span>性。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q6.itc.cn/q_70/images03/20240417/b08ecb33c62c4af98b5f0d8f939f9519.jpeg" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">Dr.David Bartlett</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">美国宾夕法尼亚州匹兹堡市阿勒格尼健康网络 (AHN) 癌症<span style="color: black;">科研</span>所主席，国际公认癌症外科<span style="color: black;">大夫</span>，腹部癌症治疗先驱，美国肿瘤外科学会前任主席。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett博士<span style="color: black;">暗示</span>，<span style="color: black;"><strong style="color: blue;">基因检测使临床<span style="color: black;">大夫</span>能够针对肿瘤内的特定突变进行靶向治疗，从而<span style="color: black;">增多</span>了治疗的有效性并改善了<span style="color: black;">病人</span>的预后。</strong></span><span style="color: black;">另外</span>，他重点<span style="color: black;">说到</span>了液体活检这一新兴技术，它<span style="color: black;">能够</span>分析血液中的循环肿瘤DNA（ctDNA），从而避免了侵入性的组织活检。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">基因检测在癌症治疗<span style="color: black;">行业</span>的应用已掀起一场革命性的变革，其中NGS技术<span style="color: black;">更加是</span>这一变革中的佼佼者。基因检测在各类癌症中发挥着越来越<span style="color: black;">要紧</span>的<span style="color: black;">功效</span>，<span style="color: black;">尤其</span>是在肺癌<span style="color: black;">行业</span>，它<span style="color: black;">已然</span><span style="color: black;">作为</span><span style="color: black;">指点</span>治疗决策的<span style="color: black;">重要</span><span style="color: black;">工具</span>。不仅如此，在多种其他癌症的治疗中，基因检测<span style="color: black;">亦</span>常被用来辅助临床诊疗，为<span style="color: black;">大夫</span><span style="color: black;">供给</span>更<span style="color: black;">精细</span>的诊疗依据。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在过去的20年里，肺癌<span style="color: black;">病人</span>生物标志物检测从<span style="color: black;">没</span>到有，临床<span style="color: black;">道理</span><span style="color: black;">持续</span>扩大，已<span style="color: black;">作为</span>常规肿瘤治疗的<span style="color: black;">要紧</span>一环。从“一刀切”式的化疗到高度定制化<span style="color: black;">精细</span>治疗<span style="color: black;">方法</span>，是基因检测及<span style="color: black;">关联</span>见解推动了这一变革。<span style="color: black;">首要</span>是认识到<span style="color: black;">有些</span>癌症存在<span style="color: black;">引起</span>蛋白激酶信号传导<span style="color: black;">失去控制</span>的改变。随后，一个革命性的概念横空出世，即利用小分子酪氨酸激酶<span style="color: black;">控制</span>剂 (TKI) 靶向酪氨酸激酶，阻止肿瘤细胞的生长和增殖。最后，<span style="color: black;">经过</span><span style="color: black;">伴同</span>基因检测实现<span style="color: black;">精细</span>治疗，<span style="color: black;">从而</span><span style="color: black;">明显</span><span style="color: black;">提高</span><span style="color: black;">病人</span><span style="color: black;">存活</span>获益。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;"><strong style="color: blue;">1. 基因检测对癌症<span style="color: black;">病人</span>有<span style="color: black;">那些</span>好处？</strong></span></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“基因检测基本上可检测到癌症中存在的所有突变。<span style="color: black;">咱们</span><span style="color: black;">经过</span>对癌症<span style="color: black;">病人</span>进行组织或液体活检并实施基因测序，可确定与该癌症<span style="color: black;">关联</span>的突变，这对<span style="color: black;">运用</span>针对这些特定突变的靶向<span style="color: black;">药品</span>非常<span style="color: black;">要紧</span>。<strong style="color: blue;">虽然并非每种癌症都有靶向<span style="color: black;">药品</span>，但随着时间的推移，越来越多的癌症已<span style="color: black;">研发</span>出针对特定突变的靶向<span style="color: black;">药品</span>。</strong>预先<span style="color: black;">认识</span>这些突变信息非常<span style="color: black;">要紧</span>。<span style="color: black;">另外</span>，<strong style="color: blue;">基因检测<span style="color: black;">能够</span><span style="color: black;">帮忙</span>我们判断<span style="color: black;">病人</span><span style="color: black;">可否</span>有遗传<span style="color: black;">原因</span>，<span style="color: black;">针对</span>有遗传<span style="color: black;">原因</span>的，<span style="color: black;">咱们</span><span style="color: black;">能够</span>给予家庭人员进行<span style="color: black;">关联</span>的筛查，实现早<span style="color: black;">发掘</span>早治疗。</strong>”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">2. 基因检测<span style="color: black;">办法</span><span style="color: black;">出现</span>了<span style="color: black;">那些</span>变化？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“<span style="color: black;">数年</span>来，<span style="color: black;">咱们</span>对肿瘤基因组学以及肿瘤中存在的突变的认知<span style="color: black;">持续</span>加深，呈现爆发式增长。以前，<span style="color: black;">咱们</span>会在肿瘤中寻找2-3个突变，但<span style="color: black;">此刻</span><span style="color: black;">咱们</span><span style="color: black;">已然</span>能够<span style="color: black;">定时</span>筛查500多个基因，以寻找专门影响癌症的已知突变。<span style="color: black;">咱们</span><span style="color: black;">评定</span>的遗传物质数量、突变数量以及检测效率都得到了<span style="color: black;">提高</span>。最初的人类基因组计划<span style="color: black;">必须</span>13年<span style="color: black;">才可</span>完成一个基因组测序（一代），<span style="color: black;">此刻</span><span style="color: black;">咱们</span><span style="color: black;">运用</span>NGS测序一天就能完成，<span style="color: black;">因此呢</span>，<span style="color: black;">咱们</span>分析这些突变的能力随时间的推移在<span style="color: black;">持续</span><span style="color: black;">加强</span>。”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q8.itc.cn/q_70/images03/20240417/f59c582fca5e42a2912819bf9ae72cf4.jpeg" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">NGS，即二代测序，又<span style="color: black;">叫作</span>高通量测序技术，能够<span style="color: black;">同期</span>对多个DNA片段进行测序，从而快速、准确地获取<span style="color: black;">海量</span>的基因组信息。这一技术不仅<span style="color: black;">能够</span>分析单个基因的序列，还能够检测<span style="color: black;">全部</span>基因组的变异<span style="color: black;">状况</span>，<span style="color: black;">因此呢</span><span style="color: black;">拥有</span>高通量、<span style="color: black;">有效</span>率的<span style="color: black;">优良</span>。在癌症<span style="color: black;">行业</span>，NGS技术为临床<span style="color: black;">大夫</span><span style="color: black;">供给</span>了前所未有的手段，使<span style="color: black;">咱们</span>能够更深入地<span style="color: black;">认识</span>肿瘤细胞的遗传特征，从而为<span style="color: black;">精细</span>治疗<span style="color: black;">供给</span>了<span style="color: black;">基本</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">3. 基因检测的最新<span style="color: black;">发展</span>是什么？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“基因检测<span style="color: black;">帮忙</span><span style="color: black;">咱们</span>在识别靶向治疗以及攻击特定<span style="color: black;">目的</span>的小分子<span style="color: black;">药品</span>方面取得巨大<span style="color: black;">发展</span>。<span style="color: black;">日前</span>，已有超过100种靶向<span style="color: black;">药品</span><span style="color: black;">获准</span>用于治疗癌症中的特定突变。<span style="color: black;">第1</span>个被<span style="color: black;">准许</span>用于特定突变的靶向<span style="color: black;">药品</span>是甲磺酸伊马替尼（格列卫），那是在2001年，自此以后靶向<span style="color: black;">药品</span><span style="color: black;">开发</span>呈现爆发式增长。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">TKI治疗<span style="color: black;">方法</span><span style="color: black;">第1</span>次临床应用是将ABL<span style="color: black;">控制</span>剂伊马替尼用于治疗慢性髓系白血病 （CML）<span style="color: black;">病人</span>。慢性髓系白血病是一种基因组相对同质的肿瘤，由BCR-ABL1融合<span style="color: black;">诱发</span>。<span style="color: black;">第1</span>次靶向治疗取得巨大成功，许多<span style="color: black;">病人</span>的症状<span style="color: black;">快速</span>得到缓解，在<span style="color: black;">药品</span>毒性降至最低的<span style="color: black;">同期</span><span style="color: black;">得到</span>了持久疗效（<span style="color: black;">乃至</span>可能治愈）。自此，人们<span style="color: black;">起始</span>寻找其它<span style="color: black;">拥有</span>激酶依赖性的肿瘤病例，以及专门干扰这些<span style="color: black;">重要</span>激酶信号通路的治疗<span style="color: black;">方法</span>，引爆了靶向<span style="color: black;">药品</span>的<span style="color: black;">开发</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">另一项基因检测的<span style="color: black;">发展</span>是ctDNA检测分析能力。<span style="color: black;">咱们</span><span style="color: black;">晓得</span>肿瘤会释放DNA到血液中，<span style="color: black;">经过</span>血液ctDNA检测<span style="color: black;">咱们</span><span style="color: black;">能够</span>识别出肿瘤突变。这是一个巨大的<span style="color: black;">优良</span>，<span style="color: black;">没</span>创、<span style="color: black;">方便</span>，<span style="color: black;">况且</span>能克服肿瘤异质性。<span style="color: black;">日前</span>，这项技术还在不断发展，<span style="color: black;">咱们</span>仍需<span style="color: black;">认识</span><span style="color: black;">更加多</span>关于液体活检<span style="color: black;">可否</span>能准确反映肿瘤活检的<span style="color: black;">状况</span>，我相信液体活检将在<span style="color: black;">将来</span>占据主导地位，并更好地反映肿瘤的<span style="color: black;">情况</span>。”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">4. 基因检测最常用于<span style="color: black;">那些</span>癌症？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“<strong style="color: blue;">任何转移性实体肿瘤和血液肿瘤都应该在诊断时进行全面的基因组分析，以便<span style="color: black;">咱们</span>寻找所有可能进行靶向治疗的靶向突变，以及随着新药上市而进行临床<span style="color: black;">实验</span>的可能性。</strong><span style="color: black;">日前</span>，基因检测最常用于肺癌和消化道等肿瘤，它<span style="color: black;">能够</span><span style="color: black;">帮忙</span><span style="color: black;">大夫</span>确定<span style="color: black;">病人</span><span style="color: black;">可否</span>会对靶向或免疫治疗产生反应。<span style="color: black;">针对</span>部分<span style="color: black;">病人</span><span style="color: black;">来讲</span>，免疫治疗可能会改善<span style="color: black;">病人</span>的<span style="color: black;">存活</span><span style="color: black;">结果</span>，<span style="color: black;">因此呢</span>，<span style="color: black;">咱们</span>要预先<span style="color: black;">晓得</span><span style="color: black;">病人</span><span style="color: black;">可否</span>有资格接受免疫治疗，这对<span style="color: black;">她们</span><span style="color: black;">来讲</span>可能是变革性的。”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">5. NGS<span style="color: black;">可否</span>是基因检测的<span style="color: black;">重点</span>工具？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“<span style="color: black;">日前</span>，NGS确实是基因检测的<span style="color: black;">重点</span><span style="color: black;">工具</span>。<span style="color: black;">咱们</span><span style="color: black;">此刻</span>是<span style="color: black;">运用</span>NGS进行肿瘤测序的。<span style="color: black;">由于</span>它能一次性检测几十<span style="color: black;">乃至</span>上百个基因，筛查<span style="color: black;">所有</span>用药的可能性，<span style="color: black;">拥有</span>通量大、<span style="color: black;">精细</span>度高、信息量丰富的优点，<span style="color: black;">能够</span>在<span style="color: black;">短期</span>对基因组进行全面的分析，<span style="color: black;">包含</span>TMB和MSI等。”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">6. NGS的<span style="color: black;">运用</span>和临床应用有什么策略？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“我认为，<span style="color: black;">日前</span>的<span style="color: black;">重要</span>策略仍然是围绕<span style="color: black;">咱们</span>所<span style="color: black;">必须</span>的靶向基因突变进行分析。例如，针对不同的肿瘤类型，<span style="color: black;">咱们</span>是<span style="color: black;">思虑</span>定制<span style="color: black;">研发</span>特定的肿瘤panel？还是<span style="color: black;">运用</span><span style="color: black;">包括</span>所有突变类型的NGS大panel？这很大程度上取决于成本、<span style="color: black;">花费</span>、保险报销以及<span style="color: black;">有些</span><span style="color: black;">繁杂</span><span style="color: black;">原因</span>。但<span style="color: black;">咱们</span>期望<span style="color: black;">出现</span>的是，<span style="color: black;">每一个</span><span style="color: black;">病患</span>转移性实体肿瘤（及血液肿瘤）的<span style="color: black;">病人</span>都<span style="color: black;">能够</span>进行NGS检测，以确定与癌症<span style="color: black;">关联</span>的所有已知肿瘤突变。<span style="color: black;">这般</span>，<span style="color: black;">咱们</span>就<span style="color: black;">持有</span>了每位接受治疗的<span style="color: black;">病人</span>全面基因组信息，方便制定当前治疗决策，以及后续<span style="color: black;">发展</span>时，<span style="color: black;">运用</span>新药、新临床<span style="color: black;">实验</span>，以及现有的免疫疗法或其他治疗<span style="color: black;">办法</span>。”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">7. 基因检测<span style="color: black;">行业</span>还有<span style="color: black;">那些</span>挑战和机遇？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“早筛，<span style="color: black;">咱们</span>感兴趣的是<span style="color: black;">怎样</span>利用这些突变来诊断和筛查癌症，<span style="color: black;">尤其</span>是当<span style="color: black;">咱们</span>谈论液体活检时。<span style="color: black;">因此呢</span>，利用某种形式的NGS<span style="color: black;">办法</span>进行肿瘤诊断和筛查，<span style="color: black;">没</span>疑是该<span style="color: black;">行业</span>一个令人振奋的焦点。<span style="color: black;">咱们</span><span style="color: black;">晓得</span>，肿瘤，<span style="color: black;">乃至</span>是<span style="color: black;">初期</span>肿瘤，会源源<span style="color: black;">持续</span>将DNA释放到血液循环系统中，<span style="color: black;">倘若</span><span style="color: black;">咱们</span><span style="color: black;">能够</span>利用这一点<span style="color: black;">做为</span>癌症筛查<span style="color: black;">办法</span>，<span style="color: black;">经过</span>NGS检测识别癌症特有突变，<span style="color: black;">那样</span><span style="color: black;">咱们</span>不仅<span style="color: black;">能够</span>确定<span style="color: black;">病人</span><span style="color: black;">身体</span><span style="color: black;">可否</span>存在癌症，还<span style="color: black;">能够</span>确定<span style="color: black;">详细</span>是哪种癌症，从而<span style="color: black;">指点</span>进一步的<span style="color: black;">检测</span>。我认为，最令人兴奋的是，<strong style="color: blue;"><span style="color: black;">咱们</span><span style="color: black;">能够</span>利用这些技术来进行癌症早筛，或检测和随访接受癌症治疗的<span style="color: black;">病人</span>，以<span style="color: black;">认识</span><span style="color: black;">她们</span><span style="color: black;">可否</span>对治疗有反应。</strong>”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">8. 该<span style="color: black;">行业</span>还有其他正在进行的<span style="color: black;">科研</span>吗？</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">David Bartlett：“有<span style="color: black;">非常多</span>令人兴奋的<span style="color: black;">科研</span>都在进行中，<span style="color: black;">例如</span>，<span style="color: black;">怎样</span><span style="color: black;">加强</span>ctDNA的检测灵敏度及<span style="color: black;">怎样</span>利用DNA甲基化、片段化等多组学检测，以进行癌症早筛和分子残留病灶（MRD）检测。我认为在不久的将来会有<span style="color: black;">海量</span>令人兴奋的<span style="color: black;">科研</span>，从生物标志物的<span style="color: black;">方向</span>为<span style="color: black;">咱们</span><span style="color: black;">供给</span><span style="color: black;">更加多</span>的癌症<span style="color: black;">科研</span><span style="color: black;">指点</span>。”</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">综合而言，基因检测尤其是NGS技术的<span style="color: black;">显现</span>，<span style="color: black;">已然</span>彻底改变了癌症治疗的面貌。它使<span style="color: black;">咱们</span>能够更深入地<span style="color: black;">认识</span>肿瘤细胞的遗传特征，为<span style="color: black;">精细</span>治疗<span style="color: black;">供给</span>了可能。<span style="color: black;">咱们</span>相信，但随着技术的<span style="color: black;">持续</span>进步和临床经验的<span style="color: black;">持续</span><span style="color: black;">累积</span>，基因检测将在<span style="color: black;">将来</span>为癌症<span style="color: black;">病人</span>和健康人群带来更为全面、<span style="color: black;">精细</span>和个性化的医疗服务。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">文案</span><span style="color: black;">源自</span>：基因Talks</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">1. 一文<span style="color: black;">认识</span>：癌症之王~胰腺癌</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">2. 攻坚肺癌EGFR耐药，第四代EGFR靶向药BLU-945的最新<span style="color: black;">科研</span>结果<span style="color: black;">颁布</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">3. 可切除肺癌<span style="color: black;">病人</span>围手术期的治疗新<span style="color: black;">选取</span>！免疫治疗新辅助/辅助治疗新临床<span style="color: black;">发展</span> | AACR、ASCO Plenary Series </p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">4. 复旦大学上海医学团队<span style="color: black;">发掘</span>叶酸诱发癌症奥秘！孕妇<span style="color: black;">弥补</span>叶酸安全吗？ </p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">5. 3大泛癌标志物：MSI-H/dMMR、TMB-H和NTRK | 6款广谱抗癌药</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">6. 最新中国恶性肿瘤流行<span style="color: black;">状况</span>分析数据<span style="color: black;">颁布</span>，液体活检驶入癌症早筛快车道！ </p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">7. “烫死”癌细胞，43℃<span style="color: black;">刚才</span>好！ </p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">8. 贝伐珠单抗、安罗替尼等抗血管生成<span style="color: black;">药品</span>临床不良反应处理 </p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">——本期完——</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;">咱们</span>（医世象，<span style="color: black;">微X</span>ID：medhealife）</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">致力于肿瘤<span style="color: black;">行业</span>的<span style="color: black;">研究</span>成果<span style="color: black;">报告</span>，以及科普知识的传播；</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">关注于肿瘤预防、早筛早诊、治疗以及<span style="color: black;">恢复</span>管理等肿瘤全生命周期管理</span></p>
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