几种癌症疫苗技术办法
<span style="color: black;">如今，癌症是一种在人类中很<span style="color: black;">平常</span>的<span style="color: black;">疾患</span>，而在更早的时候，它是在人体中很少<span style="color: black;">显现</span>的<span style="color: black;">疾患</span>。尽管某种程度上在世界各地都有<span style="color: black;">药品</span>，但不是所有<span style="color: black;">药品</span>有效能治疗所有癌症。</span><span style="color: black;"><span style="color: black;">近期</span>，在梅奥诊所<span style="color: black;">开发</span>成功了一种新的癌症疫苗，<span style="color: black;">第1</span>例<span style="color: black;">运用</span>该疫苗的癌症<span style="color: black;">病人</span>，肿瘤<span style="color: black;">已然</span><span style="color: black;">所有</span>消失了。<span style="color: black;">日前</span>，该疫苗正在临床<span style="color: black;">实验</span>中。</span><span style="color: black;"><strong style="color: blue;"><span style="color: black;"> 梅奥诊所成功<span style="color: black;">开发</span>新型抗癌疫苗 </span></strong></span><span style="color: black;">Mayo Clinic的<span style="color: black;">大夫</span><span style="color: black;">暗示</span>，这种疫苗可有效清除人体中的癌细胞。后来，他透露，在临床测试的过程中，它去除了乳腺癌<span style="color: black;">病人</span>的癌细胞。这位幸运的癌症<span style="color: black;">病人</span>，她的名字叫李·默克（Lee Mercker），住在佛罗里达。她是该临床<span style="color: black;">实验</span>的<span style="color: black;">第1</span>人。</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxA02q9zKsMVmcYbyST8r7orXlw8bhlZ00CyRXJ8c8LeGiaR87piagZcgIffUtXkD1L7d7nibTNvRBMg/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;"> <span style="color: black;">第1</span>例幸运受试者肿瘤消失 </span></strong></span><span style="color: black;">当我三月份听说我得了乳腺癌时，我感到非常震惊，<span style="color: black;">由于</span>我是健身狂热者，这一<span style="color: black;">信息</span>对我<span style="color: black;">来讲</span>简直难以置信，<span style="color: black;">况且</span>我<span style="color: black;">膳食</span>规律健康。经过<span style="color: black;">检测</span>，癌症<span style="color: black;">处在</span>DCIS零期，癌细胞并<span style="color: black;">无</span>扩散，这<span style="color: black;">寓意</span>着<span style="color: black;">疾患</span><span style="color: black;">处在</span><span style="color: black;">初期</span><span style="color: black;">周期</span>。</span><span style="color: black;">她面临着三种<span style="color: black;">选取</span>：</span><span style="color: black;">进行肿瘤切除术-切除癌细胞</span><span style="color: black;">进行乳房切除术-切除乳房</span><span style="color: black;"><span style="color: black;">或</span>参加一项可能挽救生命的疫苗的临床<span style="color: black;">实验</span>，以杀死这些细胞并防止其复发</span><h3 style="color: black; text-align: left; margin-bottom: 10px;"><span style="color: black;">最后，Lee Mercker在文件上签字，<span style="color: black;">选取</span>接受为期12周的临床<span style="color: black;">实验</span>。</span></h3>
<h3 style="color: black; text-align: left; margin-bottom: 10px;"><span style="color: black;">先采血，并进行了身体<span style="color: black;">检测</span>，合格后注射癌症疫苗。连续三次，双臂轮换注射，共四次，相隔两周。</span></h3><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxA02q9zKsMVmcYbyST8r7oibmxtf7zibVf1Qiaibg7vicYjzTiaH4TUXzzMKHdwYLPX0tMt2ibbznmrSrKg/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">就像注射流感疫苗<span style="color: black;">同样</span>简单 </span></strong></span><span style="color: black;">梅奥诊所的Chumri博士解释说，疫苗与<span style="color: black;">身体</span>的癌细胞抗争。该疫苗能够<span style="color: black;">经过</span>刺激<span style="color: black;">病人</span><span style="color: black;">自己</span>的免疫反应来攻击癌症，从而完全清除<span style="color: black;">哪些</span>癌细胞。如果<span style="color: black;">咱们</span>能够训练免疫系统来识别癌细胞或癌前细胞，<span style="color: black;">那样</span><span style="color: black;">亦</span>许免疫系统<span style="color: black;">乃至</span><span style="color: black;">能够</span>在它们发展为癌细胞之前就将其消除。</span><span style="color: black;">这种疫苗<span style="color: black;">已然</span>制备成功，现货供应，就像人类注射流感或肺炎的疫苗<span style="color: black;">同样</span>注射就<span style="color: black;">能够</span>了。</span><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxA02q9zKsMVmcYbyST8r7oicT3mywTBLtkcXNr0rx5ccLqibKcJaBHMGG7nkjlF4v955j0ibCtx2s3g/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"><span style="color: black;">Mercker说，<span style="color: black;">做为</span><span style="color: black;">实验</span>的一部分，最后她仍进行了两个乳房切除术，以<span style="color: black;">保证</span>乳腺癌完全脱离了她的身体，<span style="color: black;">亦</span>是为了获取组织来证实癌症疫苗的有效性，<span style="color: black;">科研</span>人员<span style="color: black;">经过</span><span style="color: black;">科研</span>她切除的乳房组织以<span style="color: black;">得到</span>进一步的结果，结果证实Mercker<span style="color: black;">身体</span>的癌细胞<span style="color: black;">已然</span>完全清除。</span><span style="color: black;"><span style="color: black;">日前</span>，<span style="color: black;">已然</span>有两位癌症<span style="color: black;">病人</span>在尝试该癌症疫苗治疗了，<span style="color: black;">此刻</span>正在寻找<span style="color: black;">更加多</span>的受试者，<span style="color: black;">期盼</span>这种疫苗<span style="color: black;">能够</span>完全预防癌症。梅奥诊所的<span style="color: black;">科研</span>人员透露，这种疫苗将从2020年<span style="color: black;">起始</span><span style="color: black;">持续</span>开展I、II、III期临床<span style="color: black;">科研</span>，8年内会<span style="color: black;">得到</span>FDA的<span style="color: black;">准许</span>上市，<span style="color: black;">经过</span>医院和<span style="color: black;">药店</span>向<span style="color: black;">公众</span>供应。</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">什么是癌症疫苗？</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">癌症疫苗是属于癌症免疫疗法中最新的一种治疗方式，<span style="color: black;">由于</span>它<span style="color: black;">能够</span>识别特定癌细胞上存在的蛋白质，<span style="color: black;">能够</span>阻止癌细胞生长，防止癌症复发，清除治疗后残留的癌细胞。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JfTqQLm0OnHLoNnXicgbyjibgltOjB6PJbWVfibha5HJUjG6T5HdYtm9lw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">与化疗和放疗相比，癌症疫苗<span style="color: black;">一般</span>不会产生严重的副<span style="color: black;">功效</span>，与直接杀死肿瘤细胞和<span style="color: black;">身体</span>正常快速分裂细胞的化疗和放疗不同，癌症疫苗和其他免疫疗法是<span style="color: black;">经过</span>刺激机体免疫系统而发挥其抗癌<span style="color: black;">功效</span>的，仅针对肿瘤细胞，减少副<span style="color: black;">功效</span>的<span style="color: black;">出现</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">鉴于这些特征，癌症疫苗为癌症<span style="color: black;">病人</span><span style="color: black;">供给</span>了一种更有针对性、更温和的癌症治疗<span style="color: black;">办法</span>，这种<span style="color: black;">办法</span>对身体的<span style="color: black;">害处</span>要小得多，并且<span style="color: black;">病人</span>有<span style="color: black;">期盼</span><span style="color: black;">得到</span>更好的生活质量。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">癌症疫苗的<span style="color: black;">归类</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">日前</span>，<span style="color: black;">已然</span>上市的癌症疫苗有两类，一种是预防性疫苗，如<strong style="color: blue;"><span style="color: black;">HPV宫颈癌疫苗</span></strong>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">另一种是治疗性疫苗，如<strong style="color: blue;"><span style="color: black;">Provenge（sipuleucel-T）</span></strong>，这是<span style="color: black;">全世界</span>首个<span style="color: black;">亦</span>是<span style="color: black;">日前</span><span style="color: black;">独一</span>一个<span style="color: black;">得到</span>美国FDA<span style="color: black;">准许</span>的癌症疫苗，治疗转移性前列腺癌，临床<span style="color: black;">科研</span><span style="color: black;">发掘</span>，该<span style="color: black;">药品</span>延长<span style="color: black;">病人</span>平均<span style="color: black;">存活</span>时间为<span style="color: black;">最少</span>4个月，这开创了癌症免疫治疗的新时代。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">另一</span>，古巴<span style="color: black;">准许</span>了两种肺癌疫苗，分别是<span style="color: black;"><strong style="color: blue;">一代疫苗CIMAvax-EGFR和二代疫苗Vaxira</strong></span>；日本<span style="color: black;"><strong style="color: blue;">融合细胞疫苗</strong></span><span style="color: black;">亦</span><span style="color: black;">已然</span><span style="color: black;">得到</span>厚生劳动省的认可，用于<span style="color: black;">各样</span>实体瘤的治疗；日本厚生劳动省官方宣布将 <strong style="color: blue;"><span style="color: black;">DC免疫疗法</span></strong><span style="color: black;">加入</span> A 级先进医疗技术，并已用于上万例晚期癌症病症的临床治疗；德国政府认可的<span style="color: black;"><strong style="color: blue;">DC 细胞</strong></span>制备实验室，运用 DC 免疫疗法已累积治疗数千名<span style="color: black;">病人</span>。（后文逐一介绍）</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JdWszc19STo1KviaHDr6iawbEm23u1V8W77sAyNSrccofpsuAJQMzQBFA/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">然则</span>，<span style="color: black;">因为</span>种种<span style="color: black;">原由</span>及局限性，这些疫苗并<span style="color: black;">无</span>在全世界得到广泛<span style="color: black;">运用</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">随着科学技术的<span style="color: black;">持续</span>进步，多种癌症疫苗<span style="color: black;">已然</span><span style="color: black;">逐步</span>进入临床，<span style="color: black;">按照</span>不同的技术原理，癌症疫苗又<span style="color: black;">能够</span>分为：</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">树突细胞（DC）癌症疫苗</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">重组癌症疫苗</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">抗原/佐剂癌症疫苗</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">全细胞癌疫苗</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">病毒载体和DNA癌症疫苗</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">下面，<span style="color: black;">博主</span>将为您盘点一下<span style="color: black;">日前</span>技术比较成熟且<span style="color: black;">已然</span>取得重大<span style="color: black;">发展</span>的癌症疫苗。（<span style="color: black;">经过</span>400-626-9916<span style="color: black;">得到</span><span style="color: black;">更加多</span>治疗信息）</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">古巴肺癌疫苗</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">肺癌疫苗的想法听起来很荒谬。毕竟，肺癌不是流感。<span style="color: black;">然则</span>，古巴<span style="color: black;">科研</span>人员25年的<span style="color: black;">科研</span>，使这种治疗型肺癌疫苗<span style="color: black;">此刻</span><span style="color: black;">已然</span><span style="color: black;">作为</span>现实！<span style="color: black;">初期</span>的<span style="color: black;">实验</span><span style="color: black;">显示</span>，这种治疗<span style="color: black;">办法</span><span style="color: black;">能够</span><span style="color: black;">帮忙</span>60岁以下的晚期肺癌<span style="color: black;">病人</span>平均比未接种疫苗的<span style="color: black;">病人</span>长11个月！</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">非小细胞肺癌疫苗CIMAvax在古巴和其他国家<span style="color: black;">已然</span>进行了<span style="color: black;">海量</span>的临床<span style="color: black;">实验</span>，但美国的<span style="color: black;">实验</span>目的是要疫苗联合PD-1<span style="color: black;">可否</span>更有效，能否加速免疫系统的反应，这是<span style="color: black;">第1</span>次尝试进行联合治疗。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">PD-1<span style="color: black;">控制</span>剂纳武单抗是<span style="color: black;">日前</span><span style="color: black;">全世界</span><span style="color: black;">科研</span>最热的抗癌<span style="color: black;">药品</span>之一，是一种能<span style="color: black;">诱发</span>自体免疫对抗癌症的抗体，在美国<span style="color: black;">已然</span><span style="color: black;">作为</span>非小细胞肺癌<span style="color: black;">病人</span>的标准治疗<span style="color: black;">方法</span>，<span style="color: black;">日前</span>已在中国上市并<span style="color: black;">营销</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">2018年1月，美国<span style="color: black;">第1</span>组经过初始化疗的晚期肺癌<span style="color: black;">病人</span><span style="color: black;">起始</span>进行CIMAvax疫苗联合PD-1（Opdivo，纳武单抗）治疗。<span style="color: black;">科研</span>人员Pedro Camilo Rodríguez说，这是一种非常创新的<span style="color: black;">办法</span>，对<span style="color: black;">咱们</span><span style="color: black;">来讲</span>，疫苗是一项突破性的成就。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JZlibZiamdeN9blNibGesJxpP6RJaDWZFlHHNUYp6xsbMiayDxpA7MjZtjw/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;">全世界</span>首个注册用于晚期非小细胞肺癌的疫苗--CimaVax</span></strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">近期</span>，罗斯威尔公园综合癌症中心胸部肿瘤科<span style="color: black;">专家</span>，首席<span style="color: black;">科研</span>员Grace Dy医学博士宣布<span style="color: black;">按照</span>第1<span style="color: black;">周期</span>/第2<span style="color: black;">周期</span><span style="color: black;">实验</span>的<span style="color: black;">第1</span>部分的积极结果，肺癌疫苗CIMAvax-EGF进入第二<span style="color: black;">周期</span>临床<span style="color: black;">实验</span>，将<span style="color: black;">科研</span>这种组合<span style="color: black;">办法</span><span style="color: black;">做为</span>晚期肺癌<span style="color: black;">病人</span>维持治疗的<span style="color: black;">存活</span>益处。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">但是<span style="color: black;">重视</span>，CimaVax EGF<span style="color: black;">不可</span>阻止癌症的发展，更<span style="color: black;">不可</span>治愈癌症。而是<span style="color: black;">起步</span>了一种机制，<span style="color: black;">经过</span>这种机制，癌细胞的<span style="color: black;">失去控制</span>生长和分裂更加受到限制，从而将晚期侵袭性肺癌转变为慢性<span style="color: black;">疾患</span>。<span style="color: black;">日前</span>，古巴肺癌疫苗<span style="color: black;">已然</span>在<span style="color: black;">全世界</span>80多个国家<span style="color: black;">获准</span>，国内<span style="color: black;">病人</span><span style="color: black;">亦</span><span style="color: black;">能够</span>申请从海外购买该疫苗（400-626-9916）。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">树突细胞疫苗</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">——针对<span style="color: black;">所有</span>实体瘤</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在人体血液系统中，存在一种<span style="color: black;">针对</span>人体的免疫系统起着至关<span style="color: black;">要紧</span><span style="color: black;">功效</span>的免疫细胞，即树突状细胞（Dendritic Cell，又<span style="color: black;">叫作</span>DC细胞），占总体免疫细胞的1%。DC细胞是人<span style="color: black;">身体</span>功能最强的抗原递呈细胞，<span style="color: black;">倘若</span>免疫系统中，<span style="color: black;">无</span>DC细胞携带抗原得T细胞，免疫细胞<span style="color: black;">没</span>法<span style="color: black;">自动</span>找到侵袭人体的异物（病毒、细菌、癌细胞），人体的免疫功能将大打折扣。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JgbPKtFUUjX4a8lhsOREFlQ8ibwcKyTYBBlWCM4I12pdezlpLnFwYmbA/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">DC细胞的抗原递呈<span style="color: black;">功效</span><span style="color: black;">处在</span>免疫系统中心环节，不仅能<span style="color: black;">经过</span>抗原递呈<span style="color: black;">功效</span>来教育幼稚T细胞<span style="color: black;">作为</span>抗原特异性细胞毒性T细胞（CTL）, 还可与机体其他的免疫细胞如NK细胞、NKT细胞及B细胞相互<span style="color: black;">功效</span>，激活免疫系统，识别并杀伤肿瘤。</span></p><span style="color: black;">树突细胞工作原理</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">DC细胞<span style="color: black;">做为</span><span style="color: black;">重要</span>的抗原递呈细胞，其<span style="color: black;">重点</span><span style="color: black;">功效</span>是识别并吞噬肿瘤或病毒抗原，经加工后将抗原传送至DC细胞膜表面。随后，携带抗原信息的DC细胞与幼稚型T细胞接触，将抗原信息传递给T细胞，刺激T细胞活化并扩增，产生<span style="color: black;">海量</span>的特异性识别肿瘤细胞或病毒感染细胞的T细胞。T细胞是细胞免疫主力军，占比免疫细胞58%。</span></p><span style="color: black;">树突疫苗临床<span style="color: black;">实验</span></span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">临床中正在开展许多针对癌症的治疗性疫苗接种途径。在国际临床<span style="color: black;">实验</span>官网clinicaltrials.gov中搜索术语树突细胞疫苗，有54个临床<span style="color: black;">科研</span>。这些<span style="color: black;">科研</span>中的一个<span style="color: black;">一起</span>特征是疫苗接种的<span style="color: black;">重要</span><span style="color: black;">过程</span>是将癌抗原有效呈递给T细胞。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">由于</span>DC是最有效的抗原呈递细胞，<span style="color: black;">因此呢</span>，利用它们的多样性可能产生改进的治疗性疫苗，<span style="color: black;">经过</span>400-626-9916<span style="color: black;">认识</span><span style="color: black;">更加多</span>DC疫苗信息<span style="color: black;">或</span>参与临床<span style="color: black;">实验</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JXb2TpofExicSQS7KsKGEJK4L3HGraf2quKPWWwfy8vIu4lnOzuduxgQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">树突疫苗已被国际广泛认可</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">美国FDA<span style="color: black;">准许</span>首个抗癌疫苗Provenge（sipuleucel-T）<span style="color: black;">便是</span>DC疫苗，治疗转移性前列腺癌；日本厚生劳动省官方宣布将 DC 免疫疗法<span style="color: black;">加入</span> A 级先进医疗技术，并已用于上万例晚期癌症病症的临床治疗；德国政府认可的 DC 细胞制备实验室，运用 DC 免疫疗法已累积治疗数千名<span style="color: black;">病人</span>。</span></p><span style="color: black;"><span style="color: black;">因此呢</span>，DC疫苗<span style="color: black;">已然</span>被国际医学抗肿瘤<span style="color: black;">行业</span>广泛认可，并<span style="color: black;">已然</span>应用于临床治疗，这是癌症<span style="color: black;">病人</span>治疗的新<span style="color: black;">期盼</span>，<span style="color: black;">亦</span>是治愈癌症的新<span style="color: black;">办法</span>。</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">融合细胞疫苗</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">——针对<span style="color: black;">所有</span>实体瘤</span></strong></span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">咱们</span><span style="color: black;">晓得</span>免疫系统在清理肿瘤细胞时，细胞毒性T细胞（CTL） 负责攻击癌细胞，而树突状细胞（DC）负责递呈给CTL癌细胞的抗原信息，二者相互<span style="color: black;">协同</span>，密切合作来完成杀瘤大业。DC细胞相当于信号兵，把搜索到的癌症信息传递给助理部队（CTL细胞），CTL部队<span style="color: black;">按照</span>情报来杀癌细胞。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">融合细胞疫苗是对<span style="color: black;">日前</span>的DC-CTL疗法进行改良，<span style="color: black;">此刻</span><span style="color: black;">能够</span>使癌细胞携带的多种癌抗原<span style="color: black;">作为</span>免疫系统的攻击<span style="color: black;">目的</span>，特异性更强。经过改良的融合细胞疗法<span style="color: black;">便是</span>能够让<span style="color: black;">所有</span>的肿瘤细胞抗原<span style="color: black;">所有</span>送到CTL面前，技术原理是<span style="color: black;">这般</span>的。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JHLoA4dC4Nt8VEZBa9iacEkia6J0qR6o7AnupN6b6Lnx8eqvoDIpDKgxQ/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;">融合细胞疫苗治疗原理</span>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">改良前的的DC-CTL疗法是在体外提取癌细胞的抗原（不是<span style="color: black;">所有</span>的癌抗原，仅为<span style="color: black;">有些</span>常规的抗原），再用抗原刺激体外诱导的DC细胞，使其携带抗原信息，去递呈给CTL细胞，让其<span style="color: black;">拥有</span>识别癌细胞的能力，<span style="color: black;">从而</span>杀伤癌细胞。<span style="color: black;">然则</span>，DC细胞细胞获取的抗原信息比较有限，会使得一部分癌细胞<span style="color: black;">没</span>法被识别出来。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">而改良后的融合细胞技术，是将<span style="color: black;">全部</span>癌细胞与DC细胞进行融合，<span style="color: black;">所有</span>癌症抗原信息均递呈给DC细胞。形成的融合细胞<span style="color: black;">拥有</span>癌细胞的抗原性，</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">又<span style="color: black;">拥有</span>DC细胞的递呈功能。<span style="color: black;">因此</span>，融合后的细胞<span style="color: black;">能够</span>携带着<span style="color: black;">所有</span>种类癌抗原找到CTL细胞，“<span style="color: black;">通知</span>癌细胞就是长<span style="color: black;">这般</span>的，”使其<span style="color: black;">拥有</span>癌细胞的识别与杀伤能力。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICxcpWlKVzvL25DpBdQIjj3JtQzOrT5WyZTtdgFhQZic0gHGe59NV7yDoJejTfMVtBVzfOnSXib5vQJA/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">新型病毒载体和DNA癌症疫苗</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">美国一对<span style="color: black;">专家</span>夫妇研制出一种新型的癌症疫苗，名为ImmuneFx（IFx），不是<span style="color: black;">守护</span>人体免受癌细胞快速突变的预防性疫苗，而是将基因和细胞疗法相结合，<span style="color: black;">研发</span>出来的一种“治疗性”疫苗。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">由这对夫妇<span style="color: black;">专家</span>设计的“ ImmuneFx ”治疗性疫苗是直接注射到肿瘤中，从而迫使癌细胞在其表面表达特定的细菌抗原，免疫系统能够轻易识别这种细菌抗原，使得T细胞能够有效进攻肿瘤细胞。<span style="color: black;">亦</span><span style="color: black;">便是</span>说，注射疫苗之后，激活机体免疫系统，使其在全身破坏肿瘤细胞而不<span style="color: black;">损伤</span>健康的细胞和组织。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/CwkERAMhICzdx37DJsUvCTdUAIeMWrGIC7JYOnNQQoBuKme0dElgnvtvcAm3fEZbQmFjONE8mdCAiccG6z9z08A/640?wx_fmt=jpeg&tp=webp&wxfrom=5&wx_lazy=1&wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>高科技：利用基因工程技术制备质粒DNA疫苗<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">ImmuneFx疫苗的治疗原理是，在体外<span style="color: black;">经过</span>基因工程技术来制备一种质粒DNA疫苗（化脓性链球菌emm55基因（pAc / emm55）），将疫苗<span style="color: black;">病人</span>的肿瘤细胞中，质粒DNA有个特点<span style="color: black;">便是</span><span style="color: black;">能够</span>在宿主细胞（肿瘤细胞）中表达携带的基因，emm55是一种酿脓链球菌血清分型抗原，<span style="color: black;">亦</span><span style="color: black;">便是</span>说在肿瘤细胞能表达一种细菌抗原，肿瘤细胞<span style="color: black;">因此呢</span>被标记上，而免疫系统对这个细菌抗原<span style="color: black;">尤其</span><span style="color: black;">敏锐</span>，<span style="color: black;">能够</span><span style="color: black;">快速</span>识别并调动机体的免疫细胞进行杀灭。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">*~*</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">总结</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">五十年前，麻疹，腮腺炎和风疹疫苗的<span style="color: black;">研发</span>挽救了许多生命。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">越来越多的新型疫苗<span style="color: black;">已然</span>步入临床<span style="color: black;">实验</span><span style="color: black;">周期</span>，在随后的<span style="color: black;">实验</span>中，个体化疫苗将被用于各类癌症，<span style="color: black;">持有</span>足够数量的新抗原接种疫苗<span style="color: black;">拥有</span>巨大<span style="color: black;">潜能</span>。</span></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">并且，<span style="color: black;">海量</span><span style="color: black;">科研</span>证实了癌症疫苗的可行性，相信<span style="color: black;">将来</span>随着<span style="color: black;">更加多</span>临床<span style="color: black;">科研</span>实验的开展跟进，癌症疫苗将会在癌症治疗方面发挥<span style="color: black;">要紧</span><span style="color: black;">功效</span>，离<span style="color: black;">咱们</span>打一针就让肿瘤君滚蛋的梦想<span style="color: black;">亦</span>就越来越近。</span></p><span style="color: black;">https://bigthink.com/surprising-science/breast-cancer-vaccine</span><span style="color: black;">https://www.forbes.com/sites/robinseatonjefferson/2019/10/11/mayo-breast-cancer-vaccine-could-be-available-in-less-than-a-decade/#5f4eccc127c7</span><span style="color: black;">https://morningpicker.com/entertainment/new-cancer-vaccine-founded-at-mayo-clinic-helps-to-remove-the-breast-cancer-of-floridas-women-another-achievement-for-medical-industry-28694/</span><span style="color: black;">原题：美国新型抗癌疫苗<span style="color: black;">开发</span>成功！<span style="color: black;">第1</span>例<span style="color: black;">病人</span>已宣布：肿瘤<span style="color: black;">所有</span>清除！</span><span style="color: black;"><span style="color: black;"><span style="color: black;"><span style="color: black;">源自</span>：</span></span><span style="color: black;">环宇达康</span><span style="color: black;">2019-10-18</span></span>
楼主发的这篇帖子，我觉得非常有道理。 交流如星光璀璨，点亮思想夜空。
页:
[1]