多肽定制合成：H-Ile-Pro-Pro-OH 26001-32-1
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">H-Ile-Pro-Pro-OH 是一种乳源三肽，<span style="color: black;">控制</span>血管紧张素转换酶 (<strong style="color: blue;">ACE</strong>) ，<strong style="color: blue;">IC</strong>50 为 5 μM。<span style="color: black;">拥有</span>抗高血压效果。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q8.itc.cn/images01/20240819/dde45b9db7654d369ba67a558fae0584.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">英文名：</strong>H-Ile-Pro-Pro-OH</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">别名：</strong>Ile-Pro-Pro</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">CAS号</strong>：26001-32-1</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">分子式</strong>：C16H27N3O4</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">分子量</strong>：325.4</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">等电点(PI)</strong>：6.11</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">pH=7.0时的净电荷数</strong>：-0.02</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">生物活性</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">控制</span>血管紧张素转换酶(ACE)</strong>：</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">H-Ile-Pro-Pro-OH是一种有效的ACE<span style="color: black;">控制</span>剂，其IC50值为5μM。ACE在血压调节中起着关键<span style="color: black;">功效</span>，<span style="color: black;">经过</span><span style="color: black;">控制</span>ACE，H-Ile-Pro-Pro-OH能够减少血管紧张素II的生成，从而发挥抗高血压效果。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">心血管<span style="color: black;">守护</span><span style="color: black;">功效</span></strong>：</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">身体</span><span style="color: black;">科研</span><span style="color: black;">显示</span>，H-Ile-Pro-Pro-OH能够减弱L-NAME治疗大鼠的动脉功能<span style="color: black;">阻碍</span>，并降低自发性高血压大鼠(SHR)的血压。<span style="color: black;">另外</span>，它还能减弱载脂蛋白E缺陷(apoE(-/-))小鼠的动脉粥样硬化的发展。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">其他生物活性</strong>：</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">体外<span style="color: black;">科研</span><span style="color: black;">表示</span>，H-Ile-Pro-Pro-OH可<span style="color: black;">增多</span>人脐静脉内皮细胞(HUVECs)中一氧化氮(NO)的产生，这可能与其心血管<span style="color: black;">守护</span><span style="color: black;">功效</span><span style="color: black;">相关</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">除了<span style="color: black;">以上</span><span style="color: black;">功效</span>外，H-Ile-Pro-Pro-OH还被<span style="color: black;">发掘</span><span style="color: black;">能够</span>调节肾素-血管紧张素系统（RAS），从而发挥抗高血压<span style="color: black;">功效</span>。它还<span style="color: black;">能够</span><span style="color: black;">经过</span>影响血管平滑肌细胞（VSMC）的<span style="color: black;">行径</span>来减少高血压的<span style="color: black;">危害</span>。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">另一</span>，H-Ile-Pro-Pro-OH还<span style="color: black;">表示</span>出<span style="color: black;">必定</span>的胰岛素<span style="color: black;">敏锐</span>性<span style="color: black;">加强</span><span style="color: black;">功效</span>，这可能与其在前脂肪细胞中的<span style="color: black;">功效</span><span style="color: black;">相关</span>。尽管这些肽的<span style="color: black;">详细</span>机制尚不完全清楚，但它们在抗炎和降压方面的<span style="color: black;">潜能</span><span style="color: black;">已然</span>得到了广泛的<span style="color: black;">科研</span>和认可。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">总结<span style="color: black;">来讲</span>，H-Ile-Pro-Pro-OH是一种多功能的生物活性肽，<span style="color: black;">拥有</span><span style="color: black;">明显</span>的抗高血压、抗炎和调节胰岛素<span style="color: black;">敏锐</span>性的<span style="color: black;">潜能</span>，其<span style="color: black;">重点</span><span style="color: black;">经过</span><span style="color: black;">控制</span>ACE和调节RAS系统来实现这些效果。<a style="color: black;"><span style="color: black;">返回<span style="color: black;">外链论坛： http://www.fok120.com</span>，查看<span style="color: black;">更加多</span></span></a></p>
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