肿瘤治疗中OS、PFS、ORR是什么意思？五分钟认识各评定指标
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<h2 style="color: black; text-align: left; margin-bottom: 10px;">导读</h2>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">怎样</span>延长癌症<span style="color: black;">病人</span>存活时间、<span style="color: black;">加强</span><span style="color: black;">存活</span>质量、减轻肿瘤带来的痛苦，是<span style="color: black;">评估</span>抗癌<span style="color: black;">药品</span>的<span style="color: black;">要紧</span>标准，而把这些标准落在数据上就诞生了各项“<span style="color: black;">评估</span>指标”。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">在肿瘤治疗<span style="color: black;">行业</span>，有OS、PFS、RFS、TTP、TTF、ORR、DCR、DDC等各项<span style="color: black;">评估</span>指标。<span style="color: black;">针对</span>大部分的<span style="color: black;">病人</span>和家属<span style="color: black;">来讲</span>，<span style="color: black;">经过</span>记住各项指标的含义来理解<span style="color: black;">药品</span>说明书和<span style="color: black;">药品</span>临床<span style="color: black;">实验</span>的数据，<span style="color: black;">从而</span>判断抗癌<span style="color: black;">药品</span>的优劣，是非常<span style="color: black;">要紧</span>与必要的。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">全文2022字，完整阅读可能<span style="color: black;">必须</span>5分钟。</p>
<h2 style="color: black; text-align: left; margin-bottom: 10px;">不同<span style="color: black;">周期</span>肿瘤治疗效果的<span style="color: black;">评估</span>指标</h2>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">在肿瘤多学科综合治疗的过程中，<span style="color: black;">病人</span>治疗与<span style="color: black;">恢复</span><span style="color: black;">通常</span>会经历三个台阶：</p>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">这三级台阶所<span style="color: black;">表率</span>的治疗<span style="color: black;">结果</span>是越来越好的，<span style="color: black;">每一个</span><span style="color: black;">病人</span><span style="color: black;">协同</span><span style="color: black;">大夫</span>进行积极的治疗<span style="color: black;">便是</span>为了逐个台阶向上“攀登”，争取<span style="color: black;">得到</span>最大的治疗收益。</p>
<h2 style="color: black; text-align: left; margin-bottom: 10px;">各疗效指标的<span style="color: black;">详细</span>含义</h2>
<h3 style="color: black; text-align: left; margin-bottom: 10px;">1、整体疗效<span style="color: black;">评估</span>指标</h3>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">RECIST<span style="color: black;">评估</span>标准，用于<span style="color: black;">评估</span><span style="color: black;">病人</span>的<span style="color: black;">疾患</span>整体<span style="color: black;">状况</span>。以肿瘤最长径（需≧20mm)为<span style="color: black;">测绘</span>基线；仅适用于实体瘤，血液系统、淋巴瘤除外。</p>完全缓解（CR）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">所有靶病灶消失，<span style="color: black;">没</span>新病灶<span style="color: black;">显现</span>，且肿瘤标志物正常，<span style="color: black;">最少</span>维持4周。</p>部分缓解（PR）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">靶病灶最大直径之和减少≥30%，<span style="color: black;">最少</span>维持4周。</p><span style="color: black;">疾患</span>稳定（SD）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">靶病灶最大直径之和缩小未达PR，或增大未达PD。</p><span style="color: black;">疾患</span><span style="color: black;">发展</span>（PD）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">靶病灶最大直径之和<span style="color: black;">最少</span><span style="color: black;">增多</span>≥20%，或<span style="color: black;">显现</span>新的病灶。</p>
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<h3 style="color: black; text-align: left; margin-bottom: 10px;">2、<span style="color: black;">第1</span>级台阶<span style="color: black;">关联</span>指标</h3>客观缓解率（ORR）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">一般</span>肿瘤体积缩小达到30%并能维持4周以上的<span style="color: black;">病人</span>比例，即完全缓解(CR)和部分缓解(PR)的比例之和。ORR越高说明<span style="color: black;">运用</span>该治疗<span style="color: black;">办法</span>达到肿瘤缩小的<span style="color: black;">病人</span>越多。</p><span style="color: black;">疾患</span><span style="color: black;">掌控</span>率（DCR）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">经治疗后<span style="color: black;">得到</span>缓解(CR+PR)和<span style="color: black;">疾患</span>稳定(SD)的病例数占比，即<span style="color: black;">无</span><span style="color: black;">出现</span><span style="color: black;">疾患</span><span style="color: black;">发展</span>(PD)的<span style="color: black;">病人</span>比例。</p><span style="color: black;">疾患</span><span style="color: black;">掌控</span>时间（DDC）<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">肿瘤<span style="color: black;">第1</span>次<span style="color: black;">评定</span>为</p>
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