论坛 › 天涯交友 › 近7000字流水账：成年人亦别忽略了疫苗接种（2021年版）

b1gc8v 发表于 2024-5-21 16:09:13

近7000字流水账：成年人亦别忽略了疫苗接种（2021年版）

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKzovffR84yCl0WxD0tFXDBSCBDCmux6micLGwjtDiakEwgGVG5siaurTMA/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<span style="color: black;">做为</span>主动免疫手段，接种疫苗从来都不是婴幼儿宝宝的专项，成年人<span style="color: black;">亦</span>应该接种<span style="color: black;">关联</span>疫苗以<span style="color: black;">提高</span><span style="color: black;">或</span>巩固<span style="color: black;">自己</span>的免疫力（<span style="color: black;">创立</span>起人群免疫屏障），<span style="color: black;">尤其</span>是存在<span style="color: black;">基本</span><span style="color: black;">疾患</span><span style="color: black;">或</span>免疫功能存在缺陷的人士，这<span style="color: black;">亦</span>是<span style="color: black;">守护</span>自己家人健康的有效<span style="color: black;">办法</span>，部分工作行业<span style="color: black;">亦</span>有<span style="color: black;">关联</span>的强制<span style="color: black;">需求</span>。此文以流水账的方式梳理一下成年人应该接种的<span style="color: black;">平常</span>疫苗。</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">平常</span>成年人接种的疫苗<span style="color: black;">制品</span>：</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">1、Flu 4价流感疫苗：</strong></span><span style="color: black;">世界上的</span><span style="color: black;">重点</span><span style="color: black;">制品</span>有基因重组和裂解灭活两个类型（不<span style="color: black;">举荐</span>喷鼻形式的<span style="color: black;">制品</span>），<span style="color: black;">因为</span>乙型流感毒株变异<span style="color: black;">火速</span>，毒株的制备靠得是预测，<span style="color: black;">因此</span>流感疫苗的预防效率从来只能说半斤八两，<span style="color: black;">然则</span><span style="color: black;">针对</span>婴幼儿和存在<span style="color: black;">基本</span><span style="color: black;">疾患</span>的人群，以及孕妇/哺乳期妈妈<span style="color: black;">来讲</span>，在每年流感季节来临前提前接种是非常有必要的。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKcibuTNClJMRHDFdzrfsr88hPyrIDZcvhfV1uorhSWa4gtTibKF9eO7Lw/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKGL3icibPc3jUh2uoKoYreEVpzs7Yyb8SbM2hZucXrCDGV2MicZku64y8A/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">2、Tdap破伤风/白喉/百日咳联合疫苗：</span></strong>
    </p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">针对</span>任何成年人<span style="color: black;">来讲</span>，尤其是从事高危职业，预防破伤风感染非常有必要，破伤风梭状芽孢杆菌在生活环境中广泛存在，在缺氧<span style="color: black;">前提</span>下<span style="color: black;">能够</span><span style="color: black;">海量</span>繁殖，其死亡后产生的痉挛毒素，<span style="color: black;">能够</span>与脊髓和脑干等部位的神经受体不可逆结合。虽然<span style="color: black;">引起</span>破伤风<span style="color: black;">爆发</span><span style="color: black;">必须</span>满足这些<span style="color: black;">前提</span>：开放性创伤/创口较深、伤口受到外界破伤风菌侵入、创口内有失活组织或局部组织缺血缺氧，概率虽小<span style="color: black;">然则</span>一旦发病，高达30%的死亡率是谁都不想看到的。百日咳<span style="color: black;">亦</span>不是学龄前儿童的专项，成年人<span style="color: black;">亦</span><span style="color: black;">能够</span>被感染并发病（平均发病年龄35岁），虽然症状大部分轻微不影响工作，但能传染给他人。Tdap疫苗<span style="color: black;">重点</span><span style="color: black;">制品</span>有赛诺菲巴斯德的Adacel和GSK的Boostrix，如下两图所示，在大陆地区并未引进，<span style="color: black;">亦</span><span style="color: black;">无</span>对应的国内<span style="color: black;">制品</span>，<span style="color: black;">能够</span>去香港和澳门接种</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKhicFicRqBqVuDibKoqvejEIicUqiaSfaqlu2SicxOKpdq4kcVTfcOeVar1zw/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKJnorRCyo2SIUenyHasAr3xibkYM193CGgqQLduUCo3EQr0B1TTx102g/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">3、MMR麻疹/流行性腮腺炎/风疹联合疫苗：</span></strong>这三种病原体的传播能力<span style="color: black;">处在</span>顶级水平，其中流行性腮腺炎，<span style="color: black;">亦</span>是全身性病毒感染，除了<span style="color: black;">诱发</span><span style="color: black;">平常</span>的腮腺肿胀<span style="color: black;">病痛</span>以外之外，病毒还会<span style="color: black;">长时间</span>驻留在睾丸/卵巢等部位，从而<span style="color: black;">引起</span>生殖系统受损，风疹<span style="color: black;">针对</span>孕妇<span style="color: black;">来讲</span>是恶性<span style="color: black;">疾患</span>，胎儿被感染后可<span style="color: black;">导致</span>流产、死产、早产或<span style="color: black;">病患</span>多种先天畸形<span style="color: black;">疾患</span>以及先天性风疹。成人版MMR疫苗<span style="color: black;">制品</span><span style="color: black;">重点</span>有MSD默沙东的MMR-II，在大陆地区并未引进，<span style="color: black;">能够</span>在香港和澳门接种，如下图所示：</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKJStibT5wpHs33znCOQzG5KSibt9SV6zJDKn4zAYajPX046gDSgHl2THA/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">4、Varicella水痘疫苗：</span></strong><span style="color: black;">预防VZV水痘-带状疱疹病毒感染，此病毒的传染性极强，成人感染后发病的症状<span style="color: black;">常常</span>比幼儿和儿童更为严重，死亡率<span style="color: black;">乃至</span>是儿童的30倍<span style="color: black;">上下</span>，且感染后虽然痊愈，但几乎所有人会终身携带病毒（<span style="color: black;">隐藏</span>在神经节中），老年后又会诱发令人苦不堪言的带状疱疹问题。成人版的疫苗<span style="color: black;">制品</span><span style="color: black;">重点</span>有MSD的Varivax，在大陆地区并未引进，有国产的上海生物/长春百克/上海荣盛等产品可选（<span style="color: black;">通常</span>一针200元<span style="color: black;">上下</span>），如下图所示：</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKMPpiafdCRicT1HzkibVnJd7VT8WnFxRECbMXUh8AeXfZoazzVzJa9cSwg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKich07hO0xIN6bFzAMSZ9U3IsahFSfKp8Vic5v8ibsUD1E3W9DQGf8q3yg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">5、RZV带状疱疹疫苗：</strong></span><span style="color: black;">仅</span>供50岁以上的人群接种，预防感染VZV水痘-带状疱疹病毒后<span style="color: black;">诱发</span>的苦不堪言的带状疱疹（<span style="color: black;">Herpes zoster</span>）及其并发症，<span style="color: black;">制品</span><span style="color: black;">日前</span><span style="color: black;">仅有</span><span style="color: black;">全世界</span>一家独大——GSK的<span style="color: black;">Shingrix，在大陆<span style="color: black;">已然</span>引进，如下图所示：</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKKbox5VdNhn9GSMTsBP5NxnkxMLvu6qLDvNaPkcc1Zq5hUzvQyJXHvQ/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">6、HPV人乳头瘤病毒疫苗：</span></strong>预防<span style="color: black;">平常</span>的多种HPV病毒亚型<span style="color: black;">引起</span>的皮肤<span style="color: black;">疾患</span>（<span style="color: black;">重点</span>是<span style="color: black;">花</span>菜样<img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLFpJPZRhhYPdVw1QEPBsDaRnyjwvN7PzG2zLrVibR5YdxCW1ZEE1KSmg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLFpJPZRhhYPdVw1QEPBsDaRnyjwvN7PzG2zLrVibR5YdxCW1ZEE1KSmg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">）和<span style="color: black;">关联</span>癌症（<span style="color: black;">重点</span>是女性宫颈癌，9价疫苗完全接种后，<span style="color: black;">针对</span>宫颈癌的预防效率超过90%，<span style="color: black;">然则</span>接种疫苗后<span style="color: black;">不可</span>替代常规的宫颈癌筛查，该做的体检还是得做），<span style="color: black;">日前</span>有2/4/9价三个系列的<span style="color: black;">制品</span>，2价<span style="color: black;">制品</span>能预防16、18两个病毒亚型，4价<span style="color: black;">制品</span><span style="color: black;">能够</span>预防6、11、16、18四个病毒亚型（2和4价<span style="color: black;">制品</span>在欧美国家基本被淘汰），9价<span style="color: black;">制品</span><span style="color: black;">能够</span>预防6、11、16、18、31、33、45、52、58九个病毒亚型，最优的9价<span style="color: black;">制品</span>为MSD默沙东<span style="color: black;">机构</span>独家所有—Gardasil 9，如下图所示：</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojK5n5EHhoXjwcic9t4NZTN448YhwoGlzlibtv9w1noVZgm6e9YSp1c5opQ/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">在写这篇<span style="color: black;">文案</span>的时候，<span style="color: black;">相关</span>9价<span style="color: black;">制品</span>的<span style="color: black;">专题</span><span style="color: black;">刚才</span>上了<span style="color: black;">博客</span>的热搜，如下图所示，其实就产能<span style="color: black;">来讲</span>，MSD默沙东<span style="color: black;">机构</span>完全<span style="color: black;">能够</span>满足<span style="color: black;">全部</span>中国大陆市场的消费需求，某些国内的人为<span style="color: black;">原因</span><span style="color: black;">引起</span>了<span style="color: black;">此刻</span>的“被迫<span style="color: black;">”</span>供<span style="color: black;">不该</span>求的局面，且9价<span style="color: black;">制品</span>的适宜的接种年龄段为9-45岁（男女都<span style="color: black;">能够</span>打，<span style="color: black;">亦</span>都应该打，<span style="color: black;">实质</span>上并<span style="color: black;">无</span>年龄上限的限制），只<span style="color: black;">不外</span>在26岁以前完成接种的<span style="color: black;">守护</span>效率最佳：</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894YknRUgrstWl58IShnScojKITVl4ogTRPomV7adCqWQAiadEibxHwOL0RruglbS7L71Zb3jSOJuiaKeg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">7、PCV肺炎球菌结合疫苗：</strong></span>经典牛逼<span style="color: black;">制品</span>是辉瑞的Prevnar 13，<span style="color: black;">已然</span>在<span style="color: black;">全世界</span>范围内大面积应用超过10年，<span style="color: black;">能够</span>有效应对13种高危肺炎球菌血清型（1、3、4、5、6A、6B、7F、9V、14、18C、19A、19F和23F），<span style="color: black;">实质</span>上是全年龄段人群都<span style="color: black;">能够</span>接种，而<span style="color: black;">不仅</span>是限于婴幼儿，国内<span style="color: black;">由于</span>不<span style="color: black;">恰当</span>的故意人为限制，为沃森的仿制<span style="color: black;">制品</span>留出<span style="color: black;">营销</span>空间，<span style="color: black;">因此</span>只<span style="color: black;">准许</span>给6月龄以内的婴儿<span style="color: black;">起步</span>接种流程，并经常<span style="color: black;">显现</span>断货的<span style="color: black;">状况</span>。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLcXhKD24sQJNUFkKWuDoz14OLbUUVSplk0KYFgWQ54Q3InYfK9E5ehQ/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">辉瑞的下一代<span style="color: black;">制品</span>——<span style="color: black;">Prevnar&nbsp;</span>20价肺炎球菌结合疫苗<span style="color: black;">已然</span>在2021年6月8日得到美国FDA的<span style="color: black;">准许</span>，可用于18岁以上年龄段的人群接种（预防的血清型为1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F,14, 15B, 18C, 19A, 19F, 22F, 23F和33F），与此<span style="color: black;">同期</span>MSD默沙东的竞争<span style="color: black;">制品</span>VAXNEUVANCE 15价肺炎球菌结合疫苗<span style="color: black;">亦</span>在2021年7月16日得到美国FDA的<span style="color: black;">准许</span>，<span style="color: black;">亦</span>是用于18岁以上的人群接种（预防的血清型为&nbsp;1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F和33F），这两种<span style="color: black;">制品</span><span style="color: black;">都是只需接种一次。</span><span style="color: black;">由于</span><span style="color: black;">刚才</span>上市，<span style="color: black;">因此</span>美国CDC等<span style="color: black;">关联</span><span style="color: black;">公司</span>还未更新这两种疫苗<span style="color: black;">制品</span>的接种指南。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">8、PPSV 23价肺炎球菌多糖疫苗：</span></strong>由MSD默沙东出品（国内沃森<span style="color: black;">亦</span>有对应的仿制<span style="color: black;">制品</span>），<span style="color: black;"><span style="color: black;">此刻</span>看来<span style="color: black;">已然</span>是比较鸡肋<span style="color: black;">制品</span>（尤其是在辉瑞的<span style="color: black;">Prevnar&nbsp;20价</span>肺炎球菌结合疫苗上市后）</span>
    </p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">，此款<span style="color: black;">制品</span>预防的血清型虽然多，<span style="color: black;">然则</span><span style="color: black;">因为</span>是老旧的多糖工艺，能诱发的免疫应答反应较低，只能给2岁以上的幼儿/儿童/青少年/成人接种，且免疫系统正常、<span style="color: black;">无</span><span style="color: black;">有些</span>特殊免疫缺陷类<span style="color: black;">疾患</span>的<span style="color: black;">青春</span><span style="color: black;">或</span>中年成人<span style="color: black;">亦</span>不<span style="color: black;">意见</span>接种此款疫苗。</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLx47ht2MLavCsiaSeGHeDibEOsgY83iaRPK3YRR08KWeO5ibic2yNsKoPPUQ/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">9、HepA 甲型肝炎疫苗：</strong></span>
    </p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">预防<span style="color: black;">经过</span>“粪-口”途径接触传播的甲肝病毒，虽然<span style="color: black;">此刻</span>人畜粪肥<span style="color: black;">再也不</span>直接用于农作物种植和水<span style="color: black;">制品</span>养殖（上个世纪上海地区的甲肝爆发<span style="color: black;">便是</span><span style="color: black;">由于</span>毛蚶被含甲肝病毒的粪便污染、食用前又<span style="color: black;">无</span>彻底煮熟<span style="color: black;">导致</span>），使得甲肝病例比较少见了，<span style="color: black;">然则</span><span style="color: black;">因为</span>成人感染甲肝后发病的症状<span style="color: black;">广泛</span>比较严重，还是不要掉以轻心，<span style="color: black;">平常</span>的疫苗<span style="color: black;">制品</span>有MSD默沙东的Vaqta和国产的<span style="color: black;">制品</span>（江苏艾美和北京科兴），都是灭活<span style="color: black;">制品</span>：</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLOkTuBH81gEnyhq8T9z0AYzJpSZpzVpwKGxClIsyKpXhBJvR1AzCP6A/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLBLe9jS6PibdA3B1qHibVVr7cBf8wPWN3nbNmuT4kqr9Zm2xXibaJbxGww/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">十、</span>HepB 乙型肝炎疫苗：</strong></span>这是人类历史上<span style="color: black;">第1</span>种<span style="color: black;">能够</span>预防癌症的疫苗，<span style="color: black;">况且</span>是预防杀伤力巨大的肝癌，乙肝病毒感染——肝硬化——肝癌是其形成的<span style="color: black;">重点</span><span style="color: black;">原由</span>之一（香港著名演员吴孟达的去世<span style="color: black;">便是</span>这<span style="color: black;">原由</span>，香港地区以前<span style="color: black;">亦</span>是乙肝高发地区，这<span style="color: black;">亦</span>是香港的肝癌<span style="color: black;">关联</span>的医学<span style="color: black;">科研</span>名列世界前茅的<span style="color: black;">原由</span>之一），上个世纪比较<span style="color: black;">广泛</span>的母婴垂直传播是<span style="color: black;">引起</span>当时国内新生儿<span style="color: black;">海量</span>乙肝感染的<span style="color: black;">原由</span>。<span style="color: black;">全世界</span>20亿人曾感染乙型肝炎病毒 (HBV)，其中2.57亿人是慢性感染者，其中在中国大<span style="color: black;">大概</span>8600万例，中国是世界上HBV感染人数最多的国家。<span style="color: black;">因为</span>MSD默沙东<span style="color: black;">机构</span>在80年代末90年代初的善举，基本上等于白送了基因重组乙肝疫苗专利技术和生产线给中国，<span style="color: black;">因此</span>使得<span style="color: black;">此刻</span>的新生儿乙肝感染变得很罕见。HBV的传播途径和HIV<span style="color: black;">同样</span>，<span style="color: black;">因此</span><span style="color: black;">针对</span><span style="color: black;">关联</span>高危人群<span style="color: black;">来讲</span>，还是<span style="color: black;">特别有</span>必要接种的。<span style="color: black;">平常</span>的<span style="color: black;">制品</span>是GSK的安在时和深圳康泰、大连汉信等厂商的<span style="color: black;">制品</span>：</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLRuIuNFfJVsVKBpWr2IPcxWu0LicN7SsbYJAEk2jnejBpZew6QJnGibPQ/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLDvSnjIyrN9icmNKAA2cXxECQfuvYyzjuGeEp22E0BCIPDvbGoyho2YA/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">11、Men ACWY（MCV4）四群流脑菌结合疫苗和Men B群流脑疫苗：</strong></span><span style="color: black;">日前</span>这在国内是完全的空白，<span style="color: black;">做为</span>世界上最<span style="color: black;">繁杂</span>的、最具备技术含量的疫苗<span style="color: black;">制品</span>，国内<span style="color: black;">亦</span><span style="color: black;">无</span>引进<span style="color: black;">关联</span><span style="color: black;">制品</span>，<span style="color: black;">日前</span><span style="color: black;">仅有</span>国产A群/AC群结合<span style="color: black;">制品</span>撑场子，<span style="color: black;">况且</span>是<span style="color: black;">做为</span>二类疫苗给婴幼儿接种，预防效果<span style="color: black;">特别有</span>限，虽然康希诺的MCV4<span style="color: black;">制品</span>在2021年12月29日<span style="color: black;">刚才</span><span style="color: black;">获准</span>，<span style="color: black;">然则</span>产量能否铺开以及<span style="color: black;">可否</span>能<span style="color: black;">供给</span>给成人接种还完全不确定。国内沃森出品的ACYW135四群脑膜炎球菌多糖疫苗<span style="color: black;">便是</span>“打了基本等于没打”，不<span style="color: black;">举荐</span>接种。<span style="color: black;">能够</span>去澳门和香港接种赛诺菲巴斯德的Menactra和辉瑞的Nimenrix，这两款<span style="color: black;">已然</span>在世界<span style="color: black;">重点</span>国家和地区应用超过10年，预防效果很好：</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLRGyrNtfIEiajUKialY65KCWNOMM1bN09cllwDkDYuvROZUZxVv1ShJsg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_png/pFJqZX4894bb7KRhgqEKW3PVuZy4JDNLdxGWVmJF5XlPqiblBJYPdJCCnUicrVdzsnvXRVxusaKVxFRyFu3rYaAg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">至于<span style="color: black;">Men B群流脑疫苗</span><span style="color: black;">亦</span>是近几年才<span style="color: black;">开发</span>成功，有辉瑞的Trumenba和GSK的Bexsero两种<span style="color: black;">制品</span>，<span style="color: black;">亦</span>是只能在香港和澳门等境<span style="color: black;">外区</span>区<span style="color: black;">才可</span>接种：</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">脑膜炎球菌有13个群组，能感染人类的有6个群：A群、B群、C群、X群、Y群和W群，X群<span style="color: black;">日前</span>比较罕见，<span style="color: black;">亦</span><span style="color: black;">无</span>疫苗<span style="color: black;">能够</span>预防，<span style="color: black;">脑膜炎球菌</span><span style="color: black;">一般</span>寄居于正<span style="color: black;">一般人</span>鼻咽腔，在<span style="color: black;">大概</span>5～10%的健康人鼻咽部带有本菌（<span style="color: black;">没</span>症状），秋冬季流行期高达20～70%，但带菌者90%并不发病，发病后轻则<span style="color: black;">诱发</span>鼻咽炎，严重的会<span style="color: black;">导致</span>菌血症和化脓性脊髓膜炎等问题。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">12、HIB B型流感嗜血杆菌疫苗：</span></strong>该病原体<span style="color: black;">针对</span>学龄前儿童/婴幼儿<span style="color: black;">来讲</span>是大杀器，会<span style="color: black;">诱发</span>中耳炎、鼻窦炎、结膜炎、脑膜炎、菌血症性肺炎、菌血症、蜂窝组织炎、会厌炎、化脓性关节炎、骨髓炎、心包炎等等<span style="color: black;">疾患</span>。成年人大部分都是<span style="color: black;">没</span>症状感染/携带，但<span style="color: black;">能够</span><span style="color: black;">经过</span>打喷嚏、咳嗽等传播病原体，<span style="color: black;">针对</span>某些免疫系统存在缺陷、存在特殊<span style="color: black;">疾患</span>的成年人<span style="color: black;">来讲</span><span style="color: black;">亦</span><span style="color: black;">能够</span><span style="color: black;">一样</span>致病。<span style="color: black;"><span style="color: black;">全世界</span>194个国家和地区把此疫苗<span style="color: black;">做为</span>婴幼儿免费和强制接种计划范围内，唯独中国大陆除外，仅仅是<span style="color: black;">做为</span>二类疫苗供自费<span style="color: black;">选取</span>接种。<span style="color: black;">关联</span><span style="color: black;">制品</span><span style="color: black;">重点</span>有MSD默沙东的PedvaxHIB和赛诺菲巴斯德的ActHIB，<span style="color: black;">而后</span>用于婴幼儿的4联、5联、6联疫苗<span style="color: black;">制品</span>里<span style="color: black;">亦</span><span style="color: black;">包括</span>此<span style="color: black;">成份</span>，国内兰州生物，沃森、智飞等生产商<span style="color: black;">亦</span>有婴幼儿版本的<span style="color: black;">制品</span>。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">详细</span><span style="color: black;">状况</span><span style="color: black;">详细</span>分析，成年人应该<span style="color: black;">怎样</span><span style="color: black;">选取</span>疫苗接种</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">最<span style="color: black;">基本</span>的疫苗<span style="color: black;">制品</span>，所有成年人（不分男女）只要是<span style="color: black;">无</span>疫苗<span style="color: black;">成份</span><span style="color: black;">关联</span>的禁忌症，都应该打的，<span style="color: black;">日前</span><span style="color: black;">按照</span>美国CDC的指引有四款：</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">Flu流感疫苗，每年在流感季开始前<span style="color: black;">一月</span>接种一次当年度的流感疫苗<span style="color: black;">制品</span>（新冠疫苗很可能以后<span style="color: black;">亦</span>是如此）；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">Tdap破伤风/白喉/百日咳联合疫苗，每隔10年接种一次，女性在每次怀孕后，都应该在27-36孕周之间接种一剂Tdap加强针，使得<span style="color: black;">关联</span>抗体能传给胎儿；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">新冠疫苗（赶鸭子上架<img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;">），<span style="color: black;">不外</span><span style="color: black;">因为</span>Delta和Omicron变种病毒的肆虐，使得所有新冠疫苗的<span style="color: black;">守护</span>效率大打折扣，<span style="color: black;">包含</span>之前表现最好的两款mRNA<span style="color: black;">制品</span>——辉瑞BNT的复必泰和莫德纳的mRNA-1273，即便是接种三针后，<span style="color: black;">针对</span><span style="color: black;">Omicro</span><span style="color: black;">n变种</span>的抵御还是力不从心（灭活<span style="color: black;">制品</span>就更别说了，打了后几乎等于裸奔）；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">HPV疫苗（孕妇除外，<span style="color: black;">不可</span>接种），优选9价，<span style="color: black;">尽可能</span>想办法接种，26岁之前完成接种的效果最佳，之后再接种的收益随年龄增长而<span style="color: black;">明显</span>递减，45岁后不<span style="color: black;">举荐</span>接种。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">从事医疗/教育/早教/托儿看护等行业的工作者，<span style="color: black;">身体状态正常</span>：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">HepB乙肝疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>乙肝抗体测试<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该按0-1-6月时间点，接种三针乙肝疫苗，并在完成第三针接种后2个月内检测乙肝抗体；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MMR麻疹/流行性腮腺炎/风疹联合疫苗，<span style="color: black;"><span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span></span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">Varicella水痘疫苗，<span style="color: black;"><span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，<span style="color: black;">亦</span><span style="color: black;">无</span>得过水痘<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;"><span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</span></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">MenACWY四群结合流脑疫苗，接种一针，<span style="color: black;">倘若</span>有必要，每隔5年进行加强针接种；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MenB B群流脑疫苗，接种两针，Bexsero<span style="color: black;">制品</span>是两针间隔<span style="color: black;">最少</span><span style="color: black;">一月</span>，Trumenba<span style="color: black;">制品</span>是两针间隔<span style="color: black;"><span style="color: black;">最少</span></span>
    </p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">半年。</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">19岁-26岁的<span style="color: black;">青春</span>人，准备进入大学校园<span style="color: black;">或</span>服兵役，<span style="color: black;">身体状态正常：</span></span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MMR麻疹/流行性腮腺炎/风疹联合疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">Varicella水痘疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，<span style="color: black;">亦</span><span style="color: black;">无</span>得过水痘<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MenACWY四群结合流脑疫苗，接种一针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">MenB B群流脑疫苗，接种两针，Bexsero<span style="color: black;">制品</span>是两针间隔</span><span style="color: black;"><span style="color: black;">最少</span></span><span style="color: black;"><span style="color: black;">一月</span>，Trumenba<span style="color: black;">制品</span>是两针间</span><span style="color: black;">隔</span><span style="color: black;"><span style="color: black;">最少</span></span><span style="color: black;">半年</span>。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">50岁以上的中老年人士，身体状态正常：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">针对</span>65岁以上的老年人，还<span style="color: black;">意见</span>接种一次MSD默沙东的PPSV23价肺炎球菌多糖疫苗（<span style="color: black;">在打过PCV13疫苗<span style="color: black;">最少</span>半年后实施</span>）。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">孕妇及哺乳期妈妈：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">&nbsp; &nbsp; &nbsp; &nbsp; <span style="color: black;">必定</span>要做好提前规划，<span style="color: black;">最少</span>在计划怀孕前三个月以上，该打的疫苗都得打上（参考“从事医疗/教育/早教/托儿看护等行业的工作者<span style="color: black;">”</span>这项），<span style="color: black;">尤其</span>是MMR疫苗，<span style="color: black;">而后</span><span style="color: black;">在27-36孕周之间接种一剂Tdap加强针，</span>在流感季到来之前，提前接种当年度的流感疫苗。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">身患</span>心脏病、中风或其他心血管<span style="color: black;">疾患</span>的人士：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">50岁以上的人士接种RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次<span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，</span><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再接种一次PPSV23疫苗（离上次接种<span style="color: black;">最少</span>间隔5年）。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;">身患</span>糖尿病的人士（I型和II型都<span style="color: black;">同样</span>）：</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">50岁以上的人士接种RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span></span>；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">HepB乙肝疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>乙肝抗体测试<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该按0-1-6月时间点，接种三针乙肝疫苗，并在完成第三针接种后2个月内检测乙肝抗体。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">身患</span>慢性肝病的人士：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">HepB乙肝疫苗，尚未感染乙肝病毒，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>乙肝抗体测试<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该按0-1-6月时间点，接种三针乙肝疫苗，并在完成第三针接种后2个月内检测乙肝抗体；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">HepA甲肝疫苗，<span style="color: black;"><span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，间隔半年到一年接种两针（<span style="color: black;">MSD默沙东的Vaqta</span>）；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MMR麻疹/流行性腮腺炎/风疹联合疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">Varicella水痘疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，<span style="color: black;">亦</span><span style="color: black;">无</span>得过水痘<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span>保护<span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">50岁以上的人士接种RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">身患</span>慢性肺部疾病和哮喘的人士：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>
    </p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">；</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">50岁以上的人士接种RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">身患</span>慢性肾病的人士：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，和PCV13间隔<span style="color: black;">最少</span>半年，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MMR麻疹/流行性腮腺炎/风疹联合疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">Varicella水痘疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，<span style="color: black;">亦</span><span style="color: black;">无</span>得过水痘<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">HepB乙肝疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>乙肝抗体测试<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该按0-1-6月时间点，接种三针乙肝疫苗，并在完成第三针接种后2个月内检测乙肝抗体；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">50岁以上的人士接种RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">没</span>脾<span style="color: black;">或</span>功能性<span style="color: black;">没</span>脾症<span style="color: black;">病人</span>：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，和PCV13间隔<span style="color: black;">最少</span>半年，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MMR麻疹/流行性腮腺炎/风疹联合疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">Varicella水痘疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，<span style="color: black;">亦</span><span style="color: black;">无</span>得过水痘<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">50岁以上的人士接种RZV带状疱疹疫苗（GSK的Shingrix），间隔2-6个月接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">HIB疫苗，<span style="color: black;">无</span>既往接种记录，接种一针；</p>

    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MenACWY四群结合流脑疫苗，接种一针，<span style="color: black;">倘若</span>有必要，每隔5年进行加强针接种；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MenB B群流脑疫苗，接种两针，Bexsero<span style="color: black;">制品</span>是两针间隔<span style="color: black;">一月</span>，Trumenba<span style="color: black;">制品</span>是两针间隔半年，如有必要，每隔2-3年进行加强针接种。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">免疫功能<span style="color: black;">显著</span>低下<span style="color: black;">或</span><span style="color: black;">反常</span>的人士（<span style="color: black;">例如</span>癌症<span style="color: black;">病人</span>）：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，和PCV13间隔<span style="color: black;">最少</span>半年，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">HIB疫苗，<span style="color: black;">无</span>既往接种记录，接种一针，<span style="color: black;">针对</span>实施了造血干细胞移植(HSCT)的人士，在成功移植后6-12月时间段内接种三针，每针间隔四周。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">HIV病毒感染者：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">&nbsp; &nbsp; <strong style="color: blue;">&nbsp;<span style="color: black;">倘若</span>CD4计数超过200，<span style="color: black;">意见</span>接种以下疫苗：</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，和PCV13间隔<span style="color: black;">最少</span>半年，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MMR麻疹/流行性腮腺炎/风疹联合疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">Varicella水痘疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录，<span style="color: black;">亦</span><span style="color: black;">无</span>得过水痘<span style="color: black;">或</span>抗体检测<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该间隔<span style="color: black;">一月</span>接种2针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">MenACWY四群结合流脑疫苗，接种一针，<span style="color: black;">倘若</span>有必要，每隔5年进行加强针接种；</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">HepB乙肝疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>乙肝抗体测试<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该按0-1-6月时间点，接种三针乙肝疫苗，并在完成第三针接种后2个月内检测乙肝抗体。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">&nbsp; &nbsp; &nbsp;<span style="color: black;">倘若</span>CD4计数<span style="color: black;">小于</span>200，<span style="color: black;">意见</span>接种以下疫苗：</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">辉瑞的PCV13价肺炎球菌结合疫苗，接种1针；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">19-64岁的年龄段，接种一次</span><span style="color: black;">MSD默沙东的PPSV23价肺炎球菌多糖疫苗，和PCV13间隔<span style="color: black;">最少</span>半年，</span><span style="color: black;"><span style="color: black;">针对</span>65岁以上的老年人，<span style="color: black;">意见</span>再</span><span style="color: black;">接种一次PPS</span><span style="color: black;">V23疫苗（离</span><span style="color: black;">上</span><span style="color: black;">次接种<span style="color: black;">最少</span>间隔5年</span><span style="color: black;">）</span>；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">MenACWY四群结合流脑疫苗，接种一针，<span style="color: black;">倘若</span>有必要，每隔5年进行加强针接种；</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">HepB乙肝疫苗，<span style="color: black;">倘若</span><span style="color: black;">无</span>既往接种记录<span style="color: black;">或</span>乙肝抗体测试<span style="color: black;">表示</span><span style="color: black;">无</span><span style="color: black;">守护</span><span style="color: black;">功效</span>，<span style="color: black;">那样</span>应该按0-1-6月时间点，接种三针乙肝疫苗，并在完成第三针接种后2个月内检测乙肝抗体。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">烟鬼和酒鬼，先戒烟和戒酒，要<span style="color: black;">否则</span>疫苗帮不了忙，呵呵</strong><strong style="color: blue;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"><img src="data:image/svg+xml,%3C%3Fxml version=1.0 encoding=UTF-8%3F%3E%3Csvg width=1px height=1px viewBox=0 0 1 1 version=1.1 xmlns=http://www.w3.org/2000/svg xmlns:xlink=http://www.w3.org/1999/xlink%3E%3Ctitle%3E%3C/title%3E%3Cg stroke=none stroke-width=1 fill=none fill-rule=evenodd fill-opacity=0%3E%3Cg transform=translate(-249.000000, -126.000000) fill=%23FFFFFF%3E%3Crect x=249 y=126 width=1 height=1%3E%3C/rect%3E%3C/g%3E%3C/g%3E%3C/svg%3E" style="width: 50%; margin-bottom: 20px;"></strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;"><strong style="color: blue;">更文<span style="color: black;">很难</span>，请点击下方</strong></span><span style="color: black;"><strong style="color: blue;">在看</strong></span><span style="color: black;"><strong style="color: blue;">支持一下，谢谢！</strong></span></span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">--THE END--</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">2018年3月份<span style="color: black;">起始</span>，所有新注册的<span style="color: black;">微X</span>公众号都<span style="color: black;">无</span>留言功能，要有的话，只能花大价钱迁移，此号是记录杰瑞老爸的育儿和生活<span style="color: black;">关联</span>的心得体会，暂时<span style="color: black;">无</span>必要花这个钱，有问题请发私信<span style="color: black;">信息</span>交流，我有空看到都会回复的。</p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">传播循证生活和育儿理念和知识，育儿不踩坑，请关注杰瑞老爸</strong></p>

1fy07h 发表于 2024-9-26 16:16:52

在遇到你之前，我对人世间是否有真正的圣人是怀疑的。

查看完整版本: 近7000字流水账：成年人亦别忽略了疫苗接种（2021年版）