骨髓瘤病情显现恶化能够用泊马度胺吗?
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">泊马度胺属于免疫调节剂<span style="color: black;">药品</span>,是临床继沙利度胺、来那度胺后的第三个可用于治疗多发性骨髓瘤的用药。<span style="color: black;">针对</span>病情<span style="color: black;">出现</span>恶化的患病群体<span style="color: black;">能够</span>用此药吗?副<span style="color: black;">功效</span>会不会很大?对此下文进行<span style="color: black;">关联</span>解析!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">骨髓瘤病情<span style="color: black;">显现</span>恶化<span style="color: black;">能够</span>用泊马度胺吗?</strong></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q1.itc.cn/q_70/images01/20240326/b193c1910d244535af6ecd5eb115ad3d.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">泊马度胺<span style="color: black;">能够</span><span style="color: black;">评定</span>用来治疗病情恶化的多发性骨髓瘤<span style="color: black;">病人</span>(<span style="color: black;">针对</span>两种及以上<span style="color: black;">药品</span>治疗<span style="color: black;">没</span>效或最后一次治疗两个月内病情<span style="color: black;">显现</span>恶化的病友)。此药<span style="color: black;">经过</span>对耐药性骨髓瘤细胞的靶向针对性<span style="color: black;">功效</span>,可<span style="color: black;">控制</span>细胞生长并诱导细胞凋亡,<span style="color: black;">同期</span>还能<span style="color: black;">加强</span>机体<span style="color: black;">自己</span>对肿瘤的免疫反应。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">据<span style="color: black;">关联</span>调研统计,接受泊马度胺单一治疗的病友达到客观缓解率(ORR)<span style="color: black;">达到</span>7.4%。而泊马度胺联合低剂量地塞米松治疗多发性骨髓瘤,可有29.2%的病友达到ORR。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="//q2.itc.cn/q_70/images01/20240326/1b625f71daf34128ad002223d1aef9d8.png" style="width: 50%; margin-bottom: 20px;"></p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">此药有<span style="color: black;">必定</span>的副<span style="color: black;">功效</span>,但并非所有的病人副<span style="color: black;">功效</span>都会很大,<span style="color: black;">重点</span>看个体耐受。轻者有疲乏<span style="color: black;">没</span>力、恶心呕吐、腹泻发热、感染、<span style="color: black;">呼气</span>困难等症状。重者会<span style="color: black;">显现</span>肺炎、肾脏衰竭、高钙血症、尿路感染等。部分病友还会<span style="color: black;">显现</span>中性粒细胞减少、血小板减少等症状。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">对此,泊马度胺的治疗实施<span style="color: black;">必须</span><span style="color: black;">经过</span>严谨的个体病情<span style="color: black;">认识</span>,<span style="color: black;">包含</span>对骨髓瘤病人体质耐受的<span style="color: black;">评定</span>,确定适合该药再进行。如面临严重副<span style="color: black;">功效</span>问题,则<span style="color: black;">必须</span><span style="color: black;">即时</span><span style="color: black;">调节</span>主药或剂量。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">本文来自<span style="color: black;">微X</span>公众号:MPD病友会</strong><a style="color: black;"><span style="color: black;">返回<span style="color: black;">外链论坛:http://www.fok120.com/</span>,查看<span style="color: black;">更加多</span></span></a></p>
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