j8typz 发表于 2024-6-23 22:08:32

“120W天价抗癌神药”能治愈所有肿瘤？


    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_gif/TK0ZVjXBpL6CYbiby2pRfeFh8wWyhfrGK7BO4jY4GCWH5D5G1rAQ4xrDq3EibRAfMH7RZNjRqsyojpnrTjQo5o7A/640?wx_fmt=gif&amp;wxfrom=5&amp;wx_lazy=1&amp;tp=webp" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">前篇中<span style="color: black;">咱们</span><span style="color: black;">认识</span>到</span><span style="color: black;">，细胞癌变的过程每分每秒都在<span style="color: black;">出现</span>，而身体之<span style="color: black;">因此</span>不得肿瘤，<span style="color: black;">便是</span><span style="color: black;">由于</span>免疫系统在时时刻刻的监控，<span style="color: black;">即时</span><span style="color: black;">发掘</span>基因突变的细胞，<span style="color: black;">而后</span>杀死并清除。但当免疫系统变差了，懈怠了，<span style="color: black;">不可</span><span style="color: black;">即时</span>杀死癌变的细胞，<span style="color: black;">或</span>有<span style="color: black;">有些</span><span style="color: black;">尤其</span>聪明的肿瘤细胞<span style="color: black;">发掘</span>了身体免疫系统的漏洞，伪装成正常细胞来躲避攻击，这个时候肿瘤就<span style="color: black;">出现</span>了。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/TK0ZVjXBpL4qvEjcsE0FCGHwU9xglYqwUFBFM7QwnSGPVGpS5fiaVDNxKicqia4SvF0dR8b8PpJicDUsU4T8ibEVy9Q/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">基于以上原理，<span style="color: black;">咱们</span>肿瘤免疫治疗的基本思路便是恢复免疫功能，<span style="color: black;">乃至</span>升级自己的免疫功能，把<span style="color: black;">身体</span>的免疫军队调动起来。而<span style="color: black;">日前</span><span style="color: black;">咱们</span>所熟知的免疫治疗，不外乎分为三种：</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">01</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">撕掉肿瘤细胞伪装的面纱</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">当<span style="color: black;">身体</span>的免疫系统<span style="color: black;">出现</span>问题时，肿瘤细胞就会生出一个叫做PD-L1蛋白的小手，来握住T细胞身上的PD-1，发出“我是自己人”的信号，借此来伪装自己，躲过T细胞的攻击。</span><span style="color: black;"><span style="color: black;">因此</span><span style="color: black;">咱们</span>为了砍掉肿瘤细胞的PD-L1小手，<span style="color: black;">开发</span>了PD-1/PD-L1<span style="color: black;">控制</span>剂。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">02</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">人工制造免疫细胞的产物</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">免疫细胞<span style="color: black;">便是</span>造出来<span style="color: black;">各样</span>抗体去杀伤肿瘤细胞的，<span style="color: black;">因此</span>当<span style="color: black;">自己</span>的免疫系统受损时，<span style="color: black;">咱们</span>便人为的<span style="color: black;">开发</span>了这些能够杀伤肿瘤细胞的抗体，并输进<span style="color: black;">身体</span>，<span style="color: black;">例如</span>利妥昔单抗，曲妥珠单抗都是这个机理。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">03</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;">&nbsp; &nbsp; &nbsp;&nbsp;免疫细胞疗法&nbsp; &nbsp;&nbsp; &nbsp;&nbsp;&nbsp;</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">即提取免疫细胞<span style="color: black;">按照</span>肿瘤细胞的样子去做基因改造，“120W一针的抗癌神药”CAR-T细胞治疗法，原理<span style="color: black;">便是</span>从人体提取免疫T细胞，在体外进行改造和增殖后，再回输到<span style="color: black;">身体</span>。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/TK0ZVjXBpL4qvEjcsE0FCGHwU9xglYqwfQU9HXw7CqamwiaHQ30rwLpyxHYpPqK6qicZIu1Tg3MdBlYyAHlYJ93g/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">每一条听起来都很<span style="color: black;">高挑</span>上，但<span style="color: black;">为何</span>每一种<span style="color: black;">办法</span>都会有局限性呢？<span style="color: black;">由于</span>肿瘤细胞<span style="color: black;">亦</span>在<span style="color: black;">持续</span>的变异，<span style="color: black;">持续</span>的改造自己。当你撕掉它一个面具，它就会戴上新的；当你把一种抗体做成<span style="color: black;">药品</span>来追杀它，那它就不带这个抗体了；而你<span style="color: black;">经过</span>提取并体外改造免疫细胞来杀死它，<span style="color: black;">然则</span><span style="color: black;">每一个</span>个体都是不同的，<span style="color: black;">亦</span>不会一种<span style="color: black;">办法</span><span style="color: black;">能够</span>治疗所有的肿瘤，免疫细胞治疗<span style="color: black;">日前</span>只对小部<span style="color: black;">归类</span>型肿瘤的小部分人有效。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">CAR-T<span style="color: black;">亦</span>不是万能神药，它的适应症有边界。<span style="color: black;">日前</span>，CAR-T<span style="color: black;">重点</span>用于某些血液系统癌症（如B细胞<span style="color: black;">源自</span>的血液肿瘤），对实体瘤效果<span style="color: black;">不睬</span>想。除了应用范围有限之外，<span style="color: black;">日前</span>还存在副<span style="color: black;">功效</span>的问题。一个是炎症因子风暴，另一个是神经毒性。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/TK0ZVjXBpL4qvEjcsE0FCGHwU9xglYqwib7ZlR76pEZwicibMDu8hpicUTAdZTSwSufZRxHZz2qVUIw6dO7lmC7AeA/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">除此之外免疫力不仅和免疫细胞的数量<span style="color: black;">相关</span>，但更<span style="color: black;">重要</span>的是质量，体外扩增的免疫细胞，<span style="color: black;">无</span>接触真正的敌人，<span style="color: black;">是不是</span>能真正做到<span style="color: black;">精细</span>识别？<span style="color: black;">同期</span>又怎么<span style="color: black;">保准</span>体外改造的全程操作不会污染混进细菌病</span><span style="color: black;">毒、不突变呢？</span></p><img src="https://mmbiz.qpic.cn/mmbiz_png/Ljib4So7yuWia5te5wMdlKF9EotqjvnTh7KrNCMdaT67jSPzfRia16dew7xVEanQE0jZOEgvCmNjrh793sBwV8zcg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"><strong style="color: blue;"><span style="color: black;">薄世宁<span style="color: black;">大夫</span>在《薄世宁医学通识讲义》一书中说：</span></strong>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">所有的医疗<span style="color: black;">行径</span>只起到了支持的<span style="color: black;">功效</span>，<span style="color: black;">最后</span>治愈<span style="color: black;">疾患</span>的，还是病人的自我修复能力。</span><span style="color: black;">换句话说，医疗的本质是支持生命自我修复。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">所<span style="color: black;">以避免</span>疫力才是最好的<span style="color: black;">大夫</span>，而<span style="color: black;">咱们</span>的免疫细胞是身体最忠诚的士兵，它24小时保卫着你的健康，<span style="color: black;">咱们</span>首要做的便是<span style="color: black;">提高</span>自体免疫力，<span style="color: black;">提高</span><span style="color: black;">自己</span>免疫细胞的数量与活性来达到预防肿瘤目的。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/TK0ZVjXBpL4qvEjcsE0FCGHwU9xglYqwic2fAcb8XDa1hib8UD9TenLhEUKdheibbjypbGODXhIpYhNQHibuNJiazCA/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p><span style="color: black;"><strong style="color: blue;"><span style="color: black;">上/期/回/顾</span></strong></span>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><a style="color: black;"><span style="color: black;"><span style="color: black;">肿瘤<span style="color: black;">为何</span>难以<span style="color: black;">解决</span>？</span></span></a></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><img src="https://mmbiz.qpic.cn/mmbiz_jpg/TK0ZVjXBpL6ru7Mib1rEsg5hicaFAzHxDGshpLKXHHo79Atspra0LWaicANcbbOic5YdoFYgibicvcGre8eIIQf7EZ1w/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;"></p>




杂家小谈 发表于 2024-9-2 18:06:53

谷歌网站排名优化 http://www.fok120.com/

j8typz 发表于 2024-10-27 03:15:56

你的见解真是独到，让我受益匪浅。
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