nqkk58 发表于 2024-6-24 08:05:04

抗癌重大突破!癌症亦有疫苗了?

<img src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/2Dzk8heibnBbqN09CBCBFNicbFsnW7THh9b27AJG9iasB4gEl6mwaMlHmWXXJl7leu6tUd6PXe5OMhCQQdmO0HDkw/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">据路透社<span style="color: black;">报告</span>,俄罗斯总统普京当地时间14日透露,<strong style="color: blue;">俄罗斯<span style="color: black;">专家</span>已接近研制出癌症疫苗和新一代免疫调节<span style="color: black;">药品</span></strong>,<span style="color: black;">火速</span>就<span style="color: black;">能够</span><span style="color: black;">供给</span>给<span style="color: black;">病人</span><span style="color: black;">运用</span>。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">报告</span><span style="color: black;">叫作</span>,普京当天在莫斯科出席一个关于<span style="color: black;">将来</span>技术的论坛并<span style="color: black;">发布</span>讲话,<strong style="color: blue;">“<span style="color: black;">咱们</span><span style="color: black;">已然</span>非常接近研制出癌症疫苗和新一代免疫调节<span style="color: black;">药品</span>”。</strong>“我<span style="color: black;">期盼</span>它们<span style="color: black;">火速</span>就能被有效地<span style="color: black;">功效</span>于个体治疗中。”普京说。</span></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3OnKYLviaxzTVhhNVnYI4g0nvPSfR5H79yRRVGL9H7KzOUDZU2t53JubA/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">据英国《太阳报》<span style="color: black;">网</span>3月22日<span style="color: black;">报告</span>,英国<span style="color: black;">专家</span>正在研制世界上首款肺癌疫苗。它发挥<span style="color: black;">功效</span>的机理是训练免疫系统,寻找并摧毁“携带危险信号的”蛋白质,这些蛋白质可能出<span style="color: black;">此刻</span><span style="color: black;">出现</span>内部癌变的肺细胞上。<span style="color: black;"><strong style="color: blue;">这款疫苗<span style="color: black;">能够</span>适用于约90%的肺癌。</strong></span>它不会取代戒烟而<span style="color: black;">作为</span>降低患肺癌<span style="color: black;">危害</span>的最佳方式,但<span style="color: black;">能够</span><span style="color: black;">供给</span>一条途径预防部分<span style="color: black;">初期</span>癌症。</span></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_png/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3OOtnp8TRp6dC1gDa78JoYNSZvDEKhnnLWAIm5vtwwSx7kib0gYOPYckg/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">因此</span>,<span style="color: black;">咱们</span>真的会迎来这么一天能接种抗致命肿瘤疫苗吗?</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">01</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">癌症疫苗真的能预防癌症吗?</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;">不可</span>。</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">非常多</span>人理解的疫苗,其实是“预防性疫苗”:健康人打了疫苗,就能预防某种<span style="color: black;">疾患</span>。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">咱们</span>小时候打的乙肝疫苗、卡介苗等,以及<span style="color: black;">大众</span>都很熟悉的新冠疫苗、HPV疫苗等,都属于预防性疫苗。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">然而,<span style="color: black;">这次</span><span style="color: black;">资讯</span>中<span style="color: black;">说到</span>的癌症疫苗,属于“治疗性疫苗”。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">它其实是一种治疗癌症的<span style="color: black;">办法</span>,隶属于肿瘤免疫治疗中的一种。</span></strong></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_png/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3OlzBtpcKeKDa3B4dNMDsg4nicYH4VQSGeib1hJIOdEuNpqMdaXdPCH1ug/640?wx_fmt=png&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">02</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">&nbsp; 肿瘤免疫治疗是什么意思?</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">人的<span style="color: black;">身体</span>会<span style="color: black;">持续</span>地产生癌细胞。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">但正<span style="color: black;">一般人</span>每一天新生成的癌细胞,几乎都会被人体自带的自然杀手细胞(NK细胞)杀灭。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">当免疫系统下降,自然杀手细胞变弱时,癌细胞就会占上风,久而久之,人就会得癌症。</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">肿瘤免疫治疗,<span style="color: black;">便是</span><span style="color: black;">经过</span>重新<span style="color: black;">起步</span>并维持肿瘤-免疫循环,恢复机体正常的抗肿瘤免疫反应,从而<span style="color: black;">掌控</span>与清除肿瘤的一种治疗<span style="color: black;">办法</span>。</span></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3O4FJOsfxSs2EYibkaLKJOBtBbBqzXCUYxb6cedASDPnLicEVb4e4a3lhA/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">癌症<span style="color: black;">病人</span>的免疫力<span style="color: black;">怎样</span>,会影响治疗效果及病情恶化速度。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">查出癌症没几天就去世的人,<span style="color: black;">非常多</span>时候不是<span style="color: black;">由于</span>肿瘤<span style="color: black;">引起</span>的。<strong style="color: blue;">&nbsp;而是人在极度惊恐焦虑下,会降低免疫系统在与恶性肿瘤的抗衡中所起的<span style="color: black;">功效</span>,加重病情。</strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">因此呢</span>,癌症<span style="color: black;">病人</span>提高<span style="color: black;">自己</span>免疫力,<span style="color: black;">针对</span>抗癌成功将<span style="color: black;">特别有</span><span style="color: black;">帮忙</span>。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">日前</span>比较<span style="color: black;">平常</span>的免疫治疗,有CAR-T、PD-1/PD-L1等。</span></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3OBNkONx6H6BnfGVdHNicicMEa8wpO4PoU0CDyzpER2wDdbWV600MluglA/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">03</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">“120万一针”的抗癌药:CAR-T 疗法</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">其中,<strong style="color: blue;">CAR-T<span style="color: black;">重点</span>用于血液系统肿瘤治疗</strong>,PD-1/PD-L1则只是对热肿瘤(肿瘤细胞<span style="color: black;">周边</span>聚集了<span style="color: black;">非常多</span>免疫细胞)的治疗效果较好。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">而有了癌症疫苗,就能够填补在在冷肿瘤(肿瘤细胞<span style="color: black;">周边</span><span style="color: black;">无</span><span style="color: black;">或</span><span style="color: black;">仅有</span>很少的免疫细胞)免疫治疗上的缺口。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">03</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">癌症疫苗是<span style="color: black;">怎样</span>治疗癌症的?</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">这儿</span>要先<span style="color: black;">说到</span>一对“CP”:抗原&amp;抗体。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">抗原:指能<span style="color: black;">导致</span>抗体生成的物质,是任何可诱发免疫反应的物质。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">抗体:指机体<span style="color: black;">因为</span>抗原刺激而产生的,<span style="color: black;">拥有</span><span style="color: black;">守护</span><span style="color: black;">功效</span>的蛋白质。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">癌症疫苗的原理,<span style="color: black;">便是</span>利用肿瘤抗原,诱导机体产生特异性抗肿瘤反应,激活人体<span style="color: black;">自己</span>免疫系统;</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><span style="color: black;">促进</span>免疫系统的抗体及其他防御系统主动出击,从而达到清除或<span style="color: black;">掌控</span>肿瘤的目的。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">04</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;">癌症疫苗真的<span style="color: black;">能够</span>治好癌症吗?</strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">事实上,关于癌症疫苗的<span style="color: black;">科研</span>早就<span style="color: black;">已然</span><span style="color: black;">起始</span>,并且取得了<span style="color: black;">必定</span>的成功。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">●&nbsp;黑色素瘤疫苗</span></strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">2017年7月,美国和德国的两个团队在同期《Nature》杂志上,分别刊载了关于黑色素瘤疫苗的临床<span style="color: black;">科研</span>。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">两篇<span style="color: black;">科研</span>结果均<span style="color: black;">表示</span>:在接受癌症疫苗治疗后,有半数以上的<span style="color: black;">病人</span>肿瘤完全消失;</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">即使有<span style="color: black;">少许</span><span style="color: black;">病人</span>后期复发,在联合其他免疫治疗后,肿瘤<span style="color: black;">亦</span>达到完全消失。</span></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3Oibg9NgVoH3bhTKAvam6v1qOb7GVZAmYd3Lv8HJFAzpKgbib3qtQPwib3g/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;"><strong style="color: blue;"><span style="color: black;">●&nbsp;GP2癌症疫苗(治疗乳腺癌)</span></strong></span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">2020年,圣安东尼奥乳腺癌会议上<span style="color: black;">颁布</span>了GP2癌症疫苗的Ⅱ期临床数据:</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">所有手术后接受GP2疫苗治疗的HER2/neu3 阳性乳腺癌<span style="color: black;">病人</span>,5年随访复发率为0%。</span></p><img src="https://mmbiz.qpic.cn/sz_mmbiz_jpg/2Dzk8heibnBZVPEiaqVGPmowu5NOqzvT3Oiabib0l9PxAxBhzLhwH6X59icZyngZ8ebY2oRwuyELDE0enda7Mfvkw4g/640?wx_fmt=jpeg&amp;tp=webp&amp;wxfrom=5&amp;wx_lazy=1&amp;wx_co=1" style="width: 50%; margin-bottom: 20px;">
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">Science&nbsp;Technology</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;"><span style="color: black;">不外</span>,癌症疫苗<span style="color: black;">将来</span><span style="color: black;">是不是</span>能治好所有的癌症呢?</span></strong></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">哈尔滨血液病肿瘤<span style="color: black;">科研</span>所所长马军认为:癌症疫苗能否彻底治愈癌症,仍是一个巨大的未知数。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">“理论上,癌症疫苗确实<span style="color: black;">能够</span><span style="color: black;">加强</span>免疫细胞的杀伤<span style="color: black;">功效</span>,但<span style="color: black;">通常</span>要和其他治疗手段联用。”</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">“随着DNA测序技术的进步,<span style="color: black;">咱们</span><span style="color: black;">近期</span><span style="color: black;">已然</span>看到个性化癌症疫苗的<span style="color: black;">显现</span>,”他说,“而在<span style="color: black;">将来</span>,<span style="color: black;">咱们</span>很可能会看到这种策略的爆发,<span style="color: black;">况且</span>最有效的<span style="color: black;">办法</span><span style="color: black;">便是</span>将疫苗与其它靶向<span style="color: black;">各样</span>肿瘤免疫逃逸机制的<span style="color: black;">药品</span>联合<span style="color: black;">运用</span>。”</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">在几年之前,个性化癌症疫苗的想法似乎“太科幻”了,但随着<span style="color: black;">科研</span>的发展,却越来越可能实现,西雅图 Fred Hutchinson 癌症<span style="color: black;">科研</span>中心助理临床<span style="color: black;">科研</span><span style="color: black;">分部</span>职员,<span style="color: black;">同期</span>兼任华盛顿大学的助理教授的 Seth Pollack 博士说道。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><strong style="color: blue;"><span style="color: black;">「用平常的发展眼光看待就好。<span style="color: black;">咱们</span>更应该去<span style="color: black;">连续</span>关注、<span style="color: black;">科研</span>新的癌症治疗<span style="color: black;">办法</span>。」</span></strong><span style="color: black;">十几年的<span style="color: black;">科研</span>积淀下,癌症疫苗的<span style="color: black;">关联</span>技术肯定会越来越成熟。但这并不<span style="color: black;">表率</span>它能够取代其他的癌症治疗手段,<span style="color: black;">亦</span>不必过分夸大癌症疫苗的治疗效果。</span></p>
    <p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">-END-</p>
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wrjc1hod 发表于 2024-10-12 08:56:15

感谢楼主的分享!我学到了很多。

nqkk58 发表于 2024-10-12 18:10:52

外链发布论坛学习网络优化SEO。

4zhvml8 发表于 2024-10-19 18:17:28

感谢你的精彩评论,为我的思绪打开了新的窗口。

nqkk58 发表于 2024-11-8 22:05:43

你的努力一定会被看见,相信自己,加油。
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