中山大学发掘 M1 天然病毒能精确杀灭癌细胞,是真的吗?
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">谢邀</p><span style="color: black;"><span style="color: black;">
<div style="color: black; text-align: left; margin-bottom: 10px;"><a style="color: black;">@画船听雨眠</a></div>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">和 </p><span style="color: black;"><span style="color: black;">
<div style="color: black; text-align: left; margin-bottom: 10px;"><a style="color: black;">@野合菌</a></div>
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<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">的答案都很好 <span style="color: black;">然则</span>我仍然有<span style="color: black;">有些</span>要<span style="color: black;">弥补</span>的</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">1. 关于<span style="color: black;">是不是</span>可能有用</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">这里</span><span style="color: black;">科研</span>中采用的实验动物是裸鼠(BALB/c-nu/nu)</p>
<div style="color: black; text-align: left; margin-bottom: 10px;"><img src="https://picx.zhimg.com/80/9abe568bc50210eed62f140067bd3fa8_720w.jpg?source=2c26e567" style="width: 50%; margin-bottom: 20px;"></div>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">裸鼠是在肿瘤<span style="color: black;">科研</span>中经常用到的实验动物,<span style="color: black;">由于</span>它<span style="color: black;">拥有</span>免疫缺陷,<span style="color: black;">不可</span>产生T淋巴细胞,方便进行肿瘤移植。</p><a style="color: black;">【<span style="color: black;">平常</span>问题】BALB/c Nude、NU/NU、CD-1 N</a>ude三者的区别?
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">而把裸鼠用在这项<span style="color: black;">科研</span>中,虽然使得肿瘤移植<span style="color: black;">作为</span>可能,但<span style="color: black;">亦</span>使得小鼠<span style="color: black;">没</span>法对M1病毒产生有效的免疫。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">那样</span><span style="color: black;">亦</span>就带来一个问题:正常的肿瘤病人<span style="color: black;">通常</span>并不会有免疫缺陷,在这种<span style="color: black;">状况</span>下,M1病毒输进<span style="color: black;">身体</span>,很可能会被免疫系统<span style="color: black;">快速</span>清除掉,从而<span style="color: black;">没</span>法达到治疗的效果。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">(某师姐吐槽:用裸鼠?那不<span style="color: black;">便是</span>一个看上去像<span style="color: black;">身体</span>实验的体外实验么-,-)</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">2. 关于<span style="color: black;">是不是</span>安全</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">原文中是这么交代病毒的安全性的</p>
<div style="color: black; text-align: left; margin-bottom: 10px;"><img src="data:image/svg+xml;utf8," style="width: 50%; margin-bottom: 20px;"></div>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">大意是病毒只要在马和猪之间传播,<span style="color: black;">无</span><span style="color: black;">发掘</span>和人类<span style="color: black;">疾患</span><span style="color: black;">关联</span>,<span style="color: black;">同期</span>以高滴度接种老鼠<span style="color: black;">亦</span><span style="color: black;">无</span><span style="color: black;">导致</span>老鼠发病。</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;"><span style="color: black;">然则</span><span style="color: black;">无</span><span style="color: black;">发掘</span>和人类<span style="color: black;">疾患</span><span style="color: black;">关联</span>不等于和人类<span style="color: black;">疾患</span>不<span style="color: black;">关联</span>啊!!!</p>
<p style="font-size: 16px; color: black; line-height: 40px; text-align: left; margin-bottom: 15px;">更何况作者列举的参考文献12—14里,并<span style="color: black;">无</span>做任何M1病毒对人类</p>
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感谢你的精彩评论,为我的思绪打开了新的窗口。
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